- 1. UB value code and amount
- (UMLS (HL7) C1547408) =Idea or Concept =Data type;
| - 10. ubiquitin
- [ubiquitous intracellular protein which, when covalently attached to other proteins, marks them for degradation or targeted transport. ( CSP )] (UMLS (CSP) C0041538) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
=gene product;
=parkin gene/protein |
- 2. UBB
- [This gene is involved in ubiquitin-dependent proteolysis. ( NCI )] (UMLS (NCI) C1421262) UBB Gene;
Ubiquitin B Gene =Gene or Genome | - 11. ubiquitin activating enzyme
- [A class of enzymes that catalyzes the ATP-dependent formation of a thioester bond between itself and UBIQUITIN. It then transfers the activated ubiquitin to one of the UBIQUITIN-PROTEIN LIGASES. ( MSH )] (UMLS (CSP) C0163974) =Amino Acid, Peptide, or Protein; Enzyme ;
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- 3. UBC
- [This gene plays a role in ubiquitin-dependent proteolysis. ( NCI )] (UMLS (NCI) C1421267) UBC Gene;
Ubiquitin C Gene =Gene or Genome | - 12. Ubiquitin C-Terminal Hydrolase
- [The Ubiquitin C-Terminal Hydrolases (UCH) are deubiquitinating enzymes which hydrolyze carboxyl-terminal esters and amides of ubiquitin to generate free monomeric ubiquitin from ubiquitin proproteins, but not to deubiquitinate ubiquitin-protein conjugates or disassemble polyubiquitin chains. The expression of these enzymes is tissue-specific and developmentally regulated. Members of this deubiquitinating family are also important modulators of cellular function. (NCI) ( NCI )] (UMLS (NCI) C0164005) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 4. UBD
- [This gene is involved in protein degradation and the immune response. ( NCI )] (UMLS (NCI) C1425779) UBD Gene;
Ubiquitin D Gene =Gene or Genome | - 13. ubiquitin conjugating enzyme
- [A class of enzymes that form a thioester bond to UBIQUITIN with the assistance of UBIQUITIN-ACTIVATING ENZYMES. They transfer ubiquitin to the LYSINE of a substrate protein with the assistance of UBIQUITIN-PROTEIN LIGASES. ( MSH )] (UMLS (CSP) C0084913) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 5. UBE2D2
- [This gene plays a role in a cellular mechanism for targeting abnormal or short-lived proteins for degradation. ( NCI )] (UMLS (NCI) C1421274) UBE2D2 Gene;
Ubiquitin-Conjugating Enzyme E2D 2 (UBC4/5 Homolog, Yeast) Gene =Gene or Genome | - 14. Ubiquitin Ligase Component Gene
- [Ubiquitin Ligase Genes encode eukaryotic enzymes (Ubiquitin Ligases) involved in de/ubiquitination of cellular proteins with ubiquitin through its C-terminus. Regulating the half-lives of many proteins by targeting them for degradation, ubiquitination is associated with many regulated events including protein degradation, chromatin remodeling, heat shock, cell cycle progression, differentiation, antigen presentation, retrovirus assembly, apoptosis, signal transduction, transcriptional activation, biological clocks, receptor down regulation, and endocytosis. (NCI) ( NCI )] (UMLS (NCI) C1336849) Ubiquitin Ligase Gene =Gene or Genome ;
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- 6. ubiquilin
- [ ] (UMLS (CSP) C0962589) =Amino Acid, Peptide, or Protein
| - 15. Ubiquitin Protein Ligase
- [Ubiquitin protein ligase enzymes catalyze the formation of a covalent peptide bond between the carboxy-terminal glycine of ubiquitin proteins and lysine alpha-amino group of other proteins. This typically marks proteins for either nonlysosomal proteasomal degradation or targeted transport. Ubiquitination requires sequential action of an activating enzyme, a conjugating enzyme, and a ligase. ( NCI )] (UMLS (NCI) C1256818) Ubiquitin Protein Ligase Complex =Amino Acid, Peptide, or Protein; Enzyme ;
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- 7. Ubiquinone 10
- (UMLS (NCI) C0077666) =Lipid
| - 16. Ubiquitin Specific Protease 6 (Tre-2 Oncogene) Gene
- [This gene is involved in the regulation of cellular ubiquitination. It also plays a role in promoting the recycling of endocytic vesicles to the plasma membrane. ( NCI )] (UMLS (NCI) C1421407) USP6;
USP6 Gene =Gene or Genome |
- 8. Ubiquinone Biosynthesis
- [The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme. [GOC:mah] ( GO )] (UMLS (NCI) C1157248) Ubiquinone Biosynthesis Pathway =Molecular Function
| - 17. Ubiquitin Specific Protease 8 Gene
- [This gene plays a role in ubiquitin-dependent proteolysis and cell proliferation. ( NCI )] (UMLS (NCI) C1336848) USP8;
USP8 Gene;
=Gene or Genome ;
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- 9. ubiquinylation
- [ ] (UMLS (CSP) C0599580) =Functional Concept ;
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