- 1. NR4A1
- [This gene is involved in the induction of apoptosis. It also plays a role in regulation of transcription. ( NCI )] (UMLS (NCI) C1367453) NR4A1 Gene;
Nuclear Receptor Subfamily 4, Group A, Member 1 Gene =Gene or Genome | - 2. NRAS
- [p21 N-RAS protein is encoded by the N-RAS gene. RAS proteins are involved in transmembrane signal transduction as monomeric GTP-binding proteins, with intrinsic GTPase activity, that alternate between an inactive GDP-bound form and an active GTP-bound form. RAS proteins are activated by a guanine nucleotide-exchange factor and inactivated by a GTPase-activating protein. Mitogen-stimulated RAS enhances MYC accumulation by stabilizing MYC protein. This stabilization is dependent on the RAS/RAF/MAPK pathway, which appears to inhibit the proteasome-dependent degradation of MYC. Mutations of specific amino acids activate c-RAS to transform cells and are implicated in a variety of human tumors. (from OMIM 164790, SWISS-PROT P01111, and NCI) ( NCI )] (UMLS (NCI) C0079975) =Amino Acid, Peptide, or Protein; Enzyme
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