- 1. (+)-1-Beta-D-arabinofuranosyl-5-[(E)-2-bromovi- ny1] uracil
- [A synthetic thymidine analogue with potent antiviral activity against herpes simplex and varicella zoster viruses. Sorivudine is phosphorylated into triphosphate form within the cells and this metabolite interferes with viral DNA replication by inhibiting DNA polymerase activity without been incorporated into elongating viral DNA. Due to the dangerous effects of drug-drug interactions via its metabolite, sorivudine has been removed from the market. ( NCI )] (UMLS (NCI) C0207628) =Organic Chemical; Pharmacologic Substance ;
| - 51. 17beta-(estra-1,3,5(10)-triene-3,17-diol 3-[bis(2-chloroethyl)carbamate]
- [A combination of the hormone estradiol (an estrogen) and nitrogen mustard (an anticancer drug). Used in the palliative therapy of prostate cancer. ( NCI )] (UMLS (NCI) C0014921) =Steroid; Pharmacologic Substance ;
=[AN000] ANTINEOPLASTICS;
(17beta)-Estra-1,3,5(10)-triene-3,17-diol;
Nitrogen Mustard Compound;
=Estramustine 17-(Dihydrogenphosphate) Disodium Salt;
|
- 2. (11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione
- [main glucocorticoid secreted by the adrenal cortex; its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions. ( CSP )] (UMLS (NCI) C0020268) =Steroid; Pharmacologic Substance; Hormone =[HS051] GLUCOCORTICOIDS;
Pregnenediones;
[DE200] ANTI-INFLAMMATORY, TOPICAL;
[RS100] ANTI-INFLAMMATORIES, RECTAL;
[RS202] HEMORRHOIDAL PREPARATIONS WITH STEROID;
=hydrocortisone 17-butyrate 21-propionate;
HYDROCORTISONE ACETATE;
11beta,17,21-Trihydroxypregn-4-ene-3,20-dione 17-Valerate;
11-beta,17-alpha,21-Trihydroxy-4-pregnene-3,20-dione 17-alpha-butyrate;
Hydrocortisone Cypionate;
Hydrocortisone Sodium Phosphate;
(11beta)-21-(3-Carboxy-1-oxopropyl)-11,17-dihydroxypregn-4-ene-3,20-dione, Monosodium Salt;
HYDROCORTISONE ACETONIDE;
hydrocortisone 17-butyrate 21-propionate;
HYDROCORTISONE ACETATE;
11beta,17,21-Trihydroxypregn-4-ene-3,20-dione 17-Valerate;
11-beta,17-alpha,21-Trihydroxy-4-pregnene-3,20-dione 17-alpha-butyrate;
Hydrocortisone Cypionate;
Hydrocortisone Sodium Phosphate;
(11beta)-21-(3-Carboxy-1-oxopropyl)-11,17-dihydroxypregn-4-ene-3,20-dione, Monosodium Salt;
HYDROCORTISONE POWDER (GM);
HYDROCORTISONE,NONSTERILE PWDR;
HYDROCORTISONE 10 MG;
HYDROCORTISONE 20 MG;
HYDROCORTISONE 25 MG;
HYDROCORTISONE ACETONIDE;
HYDROCORTISONE 5 MG;
Hydrocortisone 1.67 MG/ML;
HYDROCORTISONE 2.5 %;
HYDROCORTISONE 2 %;
HYDROCORTISONE 0.1 %;
HYDROCORTISONE 1 %;
HYDROCORTISONE 1 %WW;
HYDROCORTISONE 0.25 %;
HYDROCORTISONE 100 %;
HYDROCORTISONE 0.5 % | - 52. 17Beta-Cyclopentanepropionate
- [An eight-carbon ester form of Testosterone. The number of ester carbon atoms correlate with the half-life of the prodrug. Testosterone inhibits gonadotropin secretion from the pituitary gland and ablates estrogen production in the ovaries, thereby decreasing endogenous estrogen levels. In addition, this agent promotes the maintenance of male sex characteristics and is indicated for testosterone replacement in hypogonadal males. (NCI04) ( NCI )] (UMLS (NCI) C0076181) =Steroid; Pharmacologic Substance ;
=(17Beta)-17-hydroxyandrost-4-en-3-one;
=TESTOSTERONE CYPIONATE 100 MG/ML;
TESTOSTERONE CYPIONATE 50 MG/ML;
TESTOSTERONE CYPIONATE 200 MG/ML |
- 3. (11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
- [synthetic glucocorticoid with the general properties of the corticosteroids. ( CSP )] (UMLS (NCI) C0032950) =Steroid; Pharmacologic Substance ;
=[HS051] GLUCOCORTICOIDS;
Pregnadienetriols;
corticosteroid analog;
=(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione;
Prednicarbate;
PREDNISOLONE ACETATE;
Prednisolone Tebutate;
PREDNISOLONE SODIUM PHOSPHATE;
PREDNISOLONE ACETATE;
Prednisolone Tebutate;
PREDNISOLONE SODIUM PHOSPHATE;
PREDNISOLONE POWDER (GM);
PREDNISOLONE 5 MG;
PREDNISOLONE 15 MG/5ML | - 53. 17beta-Estradiol 17-Cyclopentylpropionate
- [The cypionate salt form of estradiol, the most potent, naturally produced estrogen. Estradiol cypionate diffuses through the cell membrane and binds to and subsequently activates the nuclear estrogen receptor found in the reproductive tract, breast, pituitary, hypothalamus, liver, and bone. The activated complex binds to the estrogen response element on the DNA and activates the transcription of genes involved in the functioning of the female reproductive system and secondary sex characteristics. ( NCI )] (UMLS (NCI) C0059610) =Steroid; Pharmacologic Substance; Hormone =(17beta)-Estra-1,3,5(10)-triene-3,17-diol;
=ESTRADIOL CYPIONATE 5 MG;
ESTRADIOL CYPIONATE 2 MG/ML;
ESTRADIOL CYPIONATE 5 MG/ML;
|
- 4. (11beta)-11,21-Dihydroxypregn-4-ene-3,20-dione
- [adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. ( CSP )] (UMLS (NCI) C0010124) =Steroid; Pharmacologic Substance; Hormone =[HS051] GLUCOCORTICOIDS;
| - 54. 17Beta-hydroxyestra-1,3,5(10)-trien-3-yl Acetate
- [The acetate salt form of estradiol, the most potent, naturally produced estrogen. Estradiol acetate diffuses through the cell membrane and binds to and subsequently activates the nuclear estrogen receptor found in the reproductive tract, breast, pituitary, hypothalamus, liver, and bone. The activated complex binds to the estrogen response element on the DNA and activates the transcription of genes involved in the functioning of the female reproductive system and secondary sex characteristics. ( NCI )] (UMLS (NCI) C1330622) Estradiol Acetate;
ESTRADIOL ACETATE UNIDENTIFIED;
ESTRADIOL ACETATE UNIDENTIFIED =Steroid; Pharmacologic Substance; Hormone |
- 5. (11beta)-21-(3-Carboxy-1-oxopropyl)-11,17-dihydroxypregn-4-ene-3,20-dione, Monosodium Salt
- [The sodium salt of hydrocortisone succinate with glucocorticoid property. Hydrocortisone sodium succinate is chemically similar to the endogenous hormone that stimulates anti-inflammatory and immunosuppressive activities, in addition to exhibit minor mineralocorticoid effects. This agent binds to intracellular glucocorticoid receptors and is translocated into the nucleus, where it initiates the transcription of glucocorticoid-responsive genes such as various cytokines and lipocortins. Lipocortins inhibit phospholipase A2, thereby blocking the release of arachidonic acid from membrane phospholipids and preventing the synthesis of prostaglandins and leukotrienes, both potent mediators of inflammation. ( NCI )] (UMLS (NCI) C0770560) Cortisol Sodium Succinate;
Hydrocortisone 21-Sodium Succinate;
Hydrocortisone Na Succinate;
Hydrocortisone Sodium Succinate;
HYDROCORTISONE SODIUM SUCCINATE PREPARATION;
Sodium hydrocortisone succinate =Steroid; Pharmacologic Substance ;
=(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione;
=HYDROCORTISONE SODIUM SUCCINATE 125 MG/ML;
HYDROCORTISONE SODIUM SUCCINATE 250 MG;
HYDROCORTISONE SODIUM SUCCINATE 50 MG/ML;
HYDROCORTISONE SODIUM SUCCINATE 500 MG;
HYDROCORTISONE SODIUM SUCCINATE 100 MG;
HYDROCORTISONE SODIUM SUCCINATE 1000 MG | - 55. 2'-Beta-Fluoro-2',3'-Dideoxyadenosine
- [A synthetic purine fluoro-dideoxyadenosine derivative, antiviral Lodenosine acts as a reverse transcriptase inhibitor. Although used in clinical trials for treatment of human immunodeficiency (HIV), Lodenosine induces liver or kidney damage and its use has been reconsidered. (NCI04) ( NCI )] (UMLS (NCI) C0649962) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
|
- 6. (11beta,16alpha)-21-(3,3-Dimethyl-1-oxobutoxy)-9-fluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))pregna-1,4-diene-3,20-dione
- [The hexacetonide salt form of triamcinolone, a synthetic glucocorticosteroid with immunosuppressive and anti-inflammatory activity. Triamcinolone hexacetonide binds to specific cytosolic glucocorticoid receptors and subsequently interacts with glucocorticoid receptor response element on DNA and alters gene expression. This results in an induction of the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished. ( NCI )] (UMLS (NCI) C0077004) =Steroid; Pharmacologic Substance ;
=(11beta,16alpha)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione;
9-alpha-Fluoro-11-beta,21-dihydroxy-16-alpha-isopropylidenedioxy-1,4-pregnadiene,3,20-dione =TRIAMCINOLONE HEXACETONIDE 5 MG/ML;
TRIAMCINOLONE HEXACETONIDE 20 MG/ML;
| - 56. 2-.beta.-D-Ribofuranosyl-4-thiazolecarboxamide
- (UMLS (NCI) C0092663) =Organic Chemical; Pharmacologic Substance
|
- 7. (11beta,16alpha)-9,21-Dichloro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione
- [The furoate salt form of mometasone, a synthetic topical glucocorticosteroid receptor agonist with anti-inflammatory, anti-pruritic and vasoconstrictive properties. Mometasone furoate exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression. This results in synthesis of certain anti-inflammatory proteins, while inhibiting the synthesis of certain inflammatory mediators.. Specifically, mometasone furoate appears to induce phospholipase A2 inhibitory proteins, thereby controlling the release of the inflammatory precursor arachidonic acid from phospholipid membrane by phospholipase A2. ( NCI )] (UMLS (NCI) C0066700) =Steroid; Pharmacologic Substance =Pregnadienediols;
MOMETASONE =MOMETASONE FUROATE 0.1 % | - 57. 2beta,16beta-Dipiperidino-5alpha-androstane-3alpha,17beta-diol Diacetate Dimethobromide
- [The bromide salt form of pancuronium, a synthetic, long-acting ammonio steroid muscle relaxant with curarimimetic, some antimuscarinic and sympathomimetic effects. Pancuronium bromide competitively binds to the nicotinic receptor at the neuromuscular junction, thereby preventing acetylcholine binding and resulting in skeletal muscle relaxation and paralysis. ( NCI )] (UMLS (NCI) C0030311) =Steroid; Pharmacologic Substance ;
=PANCURONIUM;
=PANCURONIUM BROMIDE 1 MG/ML;
PANCURONIUM BROMIDE 2 MG/ML |
- 8. (11beta,16alpha)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
- [synthetic glucocorticoid used in replacement therapy for adrenal insufficiency and as an anti-inflammatory and immunosuppressant in a variety of disorders. ( CSP )] (UMLS (NCI) C0040864) =Steroid; Pharmacologic Substance ;
=[HS051] GLUCOCORTICOIDS;
Pregnadienes;
Steroids, Fluorinated;
corticosteroid analog =9-alpha-Fluoro-11-beta,21-dihydroxy-16-alpha-isopropylidenedioxy-1,4-pregnadiene,3,20-dione;
TRIAMCINOLONE DIACETATE;
1,4-Pregnadiene-2,20-dione-16,17-cyclopentylidenedioxy-9-fluoro-11,21-dihydroxy-21-acetate;
9-alpha-Fluoro-11-beta,21-dihydroxy-16-alpha-isopropylidenedioxy-1,4-pregnadiene,3,20-dione;
TRIAMCINOLONE DIACETATE;
(11beta,16alpha)-21-(3,3-Dimethyl-1-oxobutoxy)-9-fluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))pregna-1,4-diene-3,20-dione;
TRIAMCINOLONE 2 MG;
TRIAMCINOLONE 8 MG;
TRIAMCINOLONE 40 MG/ML;
TRIAMCINOLONE 4 MG;
TRIAMCINOLONE 1 MG | - 58. 3beta-Hydroxy-11-oxoolean-12-en-30-oic Acid Hydrogen cis-1,2-cyclohexanedicarboxylate
- (UMLS (NCI) C0055717) =Organic Chemical; Pharmacologic Substance ;
|
- 9. (11Beta,16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
- [anti-inflammatory 9-fluoro-glucocorticoid. ( CSP )] (UMLS (NCI) C0011777) =Steroid; Pharmacologic Substance ;
=[HS051] GLUCOCORTICOIDS;
Pregnadienetriols;
Steroids, Fluorinated;
corticosteroid analog;
[DE200] ANTI-INFLAMMATORY, TOPICAL;
[OP300] ANTI-INFLAMMATORIES, TOPICAL OPHTHALMIC =9-Fluoro-11-beta,21-dihydroxy-16-alpha-methylpregna-1,4-diene-3,20-dione;
Dexamethasone acetate;
DEXAMETHASONE SODIUM PHOSPHATE;
Dexamethasone acetate;
DEXAMETHASONE SODIUM PHOSPHATE;
Dexamethasone 0.1 MG/ML;
DEXAMETHASONE 0.25 MG;
DEXAMETHASONE 0.5 MG;
DEXAMETHASONE 1 MG;
DEXAMETHASONE 1.5 MG;
DEXAMETHASONE 4 MG;
DEXAMETHASONE 6 MG;
DEXAMETHASONE 2 MG;
DEXAMETHASONE 0.5 MG/0.5ML;
DEXAMETHASONE 0.75 MG;
DEXAMETHASONE SODIUMPHOSPHATE;
DEXAMETHASONE 0.1 %;
DEXAMETHASONE 0.04 %;
DEXAMETHASONE 0.012 % | - 59. 3beta-Hydroxyandrost-5-en-17-one
- [major C19 steroid produced by the adrenal cortex; also produced in small quantities in the testis and the ovary; dehydroepiandrosterone (DHEA) can be converted to testosterone; androstenedione; estradiol; and estrone; most of DHEA is sulfated (dehydroepiandrosterone sulfate) before secretion. ( CSP )] (UMLS (NCI) C0011185) =Steroid; Pharmacologic Substance; Hormone =adrenal cortex hormone;
androgen;
[HS000] HORMONES / SYNTHETICS / MODIFIERS;
Unclassified Ingredients =DEHYDROEPIANDROSTERONE (DHEA) CAP/TAB;
|
- 10. (11beta,16alpha,17beta)-11-Hydroxy-16,17-dimethyl-17-(1-oxopropyl)androsta-1,4-dien-3-one
- [A derivative of prednisolone, a synthetic glucocorticoid with anti-inflammatory and immunosuppressive property. Upon binding to the cytosolic glucocorticoid receptor and cell entry, rimexolone activates specific glucocorticoid response elements, resulting in altered gene expression. These include induction of synthesis of anti-inflammatory protein IkappaB-alpha and inhibition of synthesis of nuclear factor kappaB (NFkappa B). As a result, pro-inflammatory cytokine production such as interleukin-1 (IL-1), IL-2 and IL-6 is down-regulated and cytotoxic T-lymphocyte activation inhibited. Therefore, an overall reduction in chronic inflammation and autoimmune reactions may be achieved. ( NCI )] (UMLS (NCI) C0140594) =Steroid; Pharmacologic Substance ;
=Pregnadienes;
[OP300] ANTI-INFLAMMATORIES, TOPICAL OPHTHALMIC;
Unclassified Ingredient Preparations;
=RIMEXOLONE 1 % | - 60. 3beta-N-1-(N-(3-(4-Aminobutyl))-1,3-diaminopropane)-7alpha,24-dihydroxy-5alpha-cholestane 24-sulfate
- (UMLS (NCI) C0213314) =Steroid; Pharmacologic Substance
|
- 11. (11beta,16beta)-9-Chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione
- [A drug being studied in the treatment of graft-versus-host disease. It belongs to a family of drugs called corticosteroids. ( NCI )] (UMLS (NCI) C0004905) =Steroid; Pharmacologic Substance; Hormone
| - 61. 9-Beta-D-arabinofuranosyl-9H-purine-6-amine Monohydrate
- [A nucleoside antibiotic isolated from the bacterium Streptomyces antibioticus with antineoplastic activity. Vidarabine inhibits DNA polymerase, resulting in the inhibition of DNA replication in tumor cells. (NCI04) ( NCI )] (UMLS (NCI) C0042646) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=adenosine;
arabinonucleoside;
[OP203] ANTIVIRALS, TOPICAL OPHTHALMIC;
=2-Fluoro-9-beta-arabinofuranosyladenine;
VIDARABINE 3 %;
|
- 12. (11beta,16beta)-9-Chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione Dipropionate
- [The dipropionate salt of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, beclomethasone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. ( NCI )] (UMLS (NCI) C0004906) =Steroid; Pharmacologic Substance ;
| - 62. beta
- [The beta-distribution is used for data that is bounded on both sides and may or may not be skewed (e.g., occurs when probabilities are estimated.) Two parameters a and b are available to adjust the curve. The mean m and variance s2 relate as follows: m = a/ (a + b) and s2 = ab/((a + b)2 (a + b + 1)). ( HL7V3.0 )] (UMLS (HL7) C1552649) =Qualitative Concept =ProbabilityDistributionType;
|
- 13. (11Beta,17beta)-9-fluoro-11,17-dihydroxy-17-methylandrost-4-en-3-one
- [A halogenated derivative of 17-alpha-methyltestosterone. Similar to testosterone, fluoxymesterone binds to and activates specific nuclear receptors, resulting in an increase in protein anabolism, a decrease in amino acid catabolism, and retention of nitrogen, potassium, and phosphorus. This agent also may competitively inhibit prolactin receptors and estrogen receptors, thereby inhibiting the growth of hormone-dependent tumor lines. Fluoxymesterone is approximately five times more potent than methyltestosterone. (NCI04) ( NCI )] (UMLS (NCI) C0016366) =Steroid; Pharmacologic Substance; Hormone =Androstenediols;
Steroids, Fluorinated;
[HS100] ANDROGENS/ANABOLICS;
=FLUOXYMESTERONE 10 MG;
FLUOXYMESTERONE 2 MG;
FLUOXYMESTERONE 5 MG;
| - 63. Beta 2 Integrin Chain
- [Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. ITGB2 encodes the integrin beta 2 chain. Mutations in the beta-2 subunit of the leukocyte cell adhesion molecule have been found to cause the autosomal recessive disorder of neutrophil function known as leukocyte adhesion deficiency(from LocusLink) ( NCI )] (UMLS (NCI) C0064830) =Amino Acid, Peptide, or Protein; Immunologic Factor; Receptor
|
- 14. (11beta-21-[4-[4-[bis(2-chloroethyl)amino]phenyl]-1-oxobutoxy]-11,17-dihydroxypregna-1,4-diene-3,20-dione
- [Ester of CHLORAMBUCIL and PREDNISOLONE used as a combination alkylating agent and synthetic steroid to treat various leukemias and other neoplasms. It causes gastrointestinal and bone marrow toxicity. ( MSH )] (UMLS (NCI) C0032949) =Steroid; Pharmacologic Substance ;
| - 64. beta 2 microglobulin
- [An 11-kDa protein associated with the outer membrane of many cells including lymphocytes. It is the small subunit of the MHC class I molecule. Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in serum, csf, and urine of normal people, and to a much greater degree in the urine and plasma of patients with tubular proteinemia, renal failure, or kidney transplants. ( MSH )] (UMLS (CSP) C0005149) =Amino Acid, Peptide, or Protein; Immunologic Factor ;
|
- 15. (17beta)-17-(1-Oxopropoxy)androst-4-en-3-one
- [A short acting oil-based injectable formulation of testosterone. Testosterone inhibits gonadotropin secretion from the pituitary gland and ablates estrogen production in the ovaries, thereby decreasing endogenous estrogen levels. In addition, this agent promotes the maintenance of male sex characteristics and is indicated for testosterone replacement in hypogonadal males. (NCI04) ( NCI )] (UMLS (NCI) C0039607) =Steroid; Pharmacologic Substance; Hormone =(17Beta)-17-hydroxyandrost-4-en-3-one;
=TESTOSTERONE PROPIONATE POWDER (GM);
TESTOSTERONE PROPIONATE 100 MG/ML;
TESTOSTERONE PROPIONATE 50 MG/ML;
TESTOSTERONE PROPIONATE 25 MG;
TESTOSTERONE PROPIONATE 25 MG/ML | - 65. beta adrenergic agent
- [drug that selectively binds to and activates beta adrenergic receptors. ( CSP )] (UMLS (CSP) C0178503) =Pharmacologic Substance ;
=adrenergic agent;
|
- 16. (17Beta)-17-hydroxy-17-methylandrost-4-en-3-one
- [A methylated synthetic androgen receptor agonist with anabolic effects. Methyltestosterone, mimicking testosterone, binds to cytosolic androgen receptors, and the subsequent nuclear transfer of the ligand-receptor complex induces transcription initiation of androgen responsive genes. The gene products are responsible for normal growth and development of male sex organs and secondary sex characteristics. The agent also causes retention of nitrogen, sodium, potassium, phosphorus, as well as calcium. ( NCI )] (UMLS (NCI) C0025826) =Steroid; Pharmacologic Substance; Hormone =(17Beta)-17-hydroxyandrost-4-en-3-one;
[HS100] ANDROGENS/ANABOLICS =METHYLTESTOSTERONE POWDER (GM);
METHYLTESTOSTERONE 1.25 MG;
METHYLTESTOSTERONE 2.5 MG;
METHYLTESTOSTERONE 25 MG;
METHYLTESTOSTERONE 5 MG;
METHYLTESTOSTERONE 10 MG;
| - 66. beta adrenergic receptor
- [coupled through the G protein Gs to adenylate cyclase such that extracellular stimulation results in increased intracellular cyclic AMP; beta-1 mediates lipolysis and cardiostimulation, beta-2 broncho- and vaso- dilation. ( CSP )] (UMLS (CSP) C0034785) =Amino Acid, Peptide, or Protein; Receptor ;
=adrenergic receptor;
|
- 17. (17Beta)-17-hydroxyandrost-4-en-3-one
- [major androgenic hormone produced by the Leydig cells of the testes. ( CSP )] (UMLS (NCI) C0039601) =Steroid; Pharmacologic Substance; Hormone =androgen;
Androstenols;
[HS100] ANDROGENS/ANABOLICS;
=(17Beta)-17-hydroxy-17-methylandrost-4-en-3-one;
(17beta)-17-(1-Oxopropoxy)androst-4-en-3-one;
17Beta-Cyclopentanepropionate;
Testosterone enanthate;
(17beta)-17-(1-Oxopropoxy)androst-4-en-3-one;
17Beta-Cyclopentanepropionate;
Testosterone enanthate;
TESTOSTERONE POWDER (GM);
TESTOSTERONE 100 MG/ML;
TESTOSTERONE 25 MG;
TESTOSTERONE 25 MG/ML;
TESTOSTERONE 75 MG;
TESTOSTERONE 50 MG/ML;
TESTOSTERONE 5 GM;
TESTOSTERONE 2.5 GM;
TESTOSTERONE 4 MG;
TESTOSTERONE 6 MG;
TESTOSTERONE 2.5 MG;
TESTOSTERONE 5 MG | - 67. Beta Adrenergic Receptor Gene
- [Expressed in effector tissues innervated by postganglionic sympathetic adrenergic fibers, Beta Adrenergic Receptor Genes encode Beta Adrenergic Receptors, one of two major classes of adrenergic receptors (alpha and beta) based on their reactions to norepinephrine and epinephrine, on cellular effects of receptor activation, and on relative affinities and reactions to synthetic blocking or stimulating agents. Beta-adrenergic receptors respond to blocking agents such as propranolol and to activating agents such as isoproterenol. Beta-1 type receptors mediate lipolysis and increase cardiac rate and force of contraction; beta-2 type receptor activation promotes bronchial and vascular smooth muscle relaxation. When coupled to adenylate cyclase through Gs protein, Beta Adrenergic Receptor stimulation results in increased intracellular cyclic AMP. (NCI) ( NCI )] (UMLS (NCI) C1332546) =Gene or Genome
|
- 18. (17beta)-2-Methoxyestra-1,3,5(10)-triene-3,17-diol
- [2ME2. A drug derived from estrogen that belongs to the family of drugs called angiogenesis inhibitors. It prevents the formation of new blood vessels that tumors need in order to grow. ( NCI )] (UMLS (NCI) C0046319) =Steroid; Pharmacologic Substance
| - 68. beta adrenergic receptor kinase
- [G-protein-coupled receptor kinases that mediate agonist-dependent PHOSPHORYLATION and desensitization of BETA-ADRENERGIC RECEPTORS. ( MSH )] (UMLS (CSP) C0053379) =Amino Acid, Peptide, or Protein; Enzyme; Receptor =alcohol phosphotransferase;
|
- 19. (17beta)-Estra-1,3,5(10)-triene-3,17-diol
- [generally refers to the 17-beta-isomer of estradiol, an aromatized C18 steroid with hydroxyl group at 3-beta- and 17-beta-position; estradiol-17-beta is the most potent form of mammalian estrogenic steroids. ( CSP )] (UMLS (NCI) C0014912) =Steroid; Pharmacologic Substance; Hormone =(17beta)-Estra-1,3,5(10)-triene-3,17-diol;
Estrenes;
[HS300] ESTROGENS;
[GU500] ESTROGENS, VAGINAL =17beta-(estra-1,3,5(10)-triene-3,17-diol 3-[bis(2-chloroethyl)carbamate];
17beta-Estradiol 17-Cyclopentylpropionate;
ESTRADIOL VALERATE;
Estradiol Phosphate Polymer;
ESTRADIOL 17-BETA 1 MG;
(17beta)-Estra-1,3,5(10)-triene-3,17-diol;
17beta-Estradiol 17-Cyclopentylpropionate;
ESTRADIOL VALERATE;
84 HR Estradiol 0.00156 MG/HR Transdermal Patch [Vivelle-Dot];
84 HR Estradiol 0.00312 MG/HR Transdermal Patch [Vivelle-Dot];
84 HR Estradiol 0.00417 MG/HR Transdermal Patch [Vivelle-Dot];
84 HR Estradiol 0.00208 MG/HR Transdermal Patch [Vivelle-Dot];
ESTRADIOL MISC. POWDER (GM);
ESTRADIOL 0.5 MG;
ESTRADIOL 1 MG;
ESTRADIOL 2 MG;
ESTRADIOL 0.025 MG;
84 HR Estradiol 0.00104 MG/HR Transdermal Patch [Vivelle-Dot];
ESTRADIOL 0.01 %;
ESTRADIOL 0.0375 MG;
ESTRADIOL 0.05 MG;
ESTRADIOL 0.075 MG;
ESTRADIOL 0.1 MG;
ESTRADIOL 25 MCG | - 69. beta alanine
- [An amino acid formed in vivo by the degradation of dihydrouracil and carnosine. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing GAMMA-AMINOBUTYRIC ACID. A rare genetic disorder, hyper-beta-alaninemia, has been reported. ( MSH )] (UMLS (CSP) C0000392) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Biologically Active Substance
|
- 20. (17beta)-Estra-1,3,5(10)-triene-3,17-diol 3-Benzoate
- [The synthetic benzoate ester of estradiol, a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. As the primary, most potent estrogen hormone produced by the ovaries, estradiol binds to and activates specific nuclear receptors. This agent exhibits mild anabolic and metabolic properties, and increases blood coagulability. (NCI04) ( NCI )] (UMLS (NCI) C0167626) =Steroid; Pharmacologic Substance; Hormone
| - 70. beta alanine receptor
- [ ] (UMLS (CSP) C0598529) =Amino Acid, Peptide, or Protein; Receptor
|
- 21. (17beta)-Estra-1,3,5(10)-triene-3,17-diol Dipropanoate
- [The synthetic dipropionate ester of estradiol, a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. As the primary, most potent estrogen hormone produced by the ovaries, estradiol binds to and activates specific nuclear receptors. This agent exhibits mild anabolic and metabolic properties, and increases blood coagulability. (NCI04) ( NCI )] (UMLS (NCI) C0059618) =Steroid; Pharmacologic Substance; Hormone
| - 71. beta aminopropionitrile
- [3-aminopropanenitrile; reagent used as an intermediate in the manufacture of beta-alanine and pantothenic acid. ( CSP )] (UMLS (CSP) C0085885) =Organic Chemical; Hazardous or Poisonous Substance =Mutagen;
alkyl nitrile |
- 22. (3-beta)-cholest-5-en-3-ol 4-(bis(2-chloroethyl)amino)benzeneacetate
- [A steroidal nitrogen mustard with antineoplastic and mutagenic activities. After attachment to cell-surface steroid receptors and uptake, phenesterin enters the nucleus where it alkylates macromolecules, resulting in decreased cell proliferation. (NCI04) ( NCI )] (UMLS (NCI) C0070556) =Organic Chemical; Pharmacologic Substance ;
| - 72. beta amylase
- [An enzyme that catalyzes the hydrolysis of 1,4-alpha-glycosidic linkages in starch, glycogen, and related polysaccharides and oligosaccharides so as to remove successive beta-maltose units from the non-reducing ends of the chains. EC 3.2.1.2. ( MSH )] (UMLS (CSP) C0005194) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 23. (3-beta,17-alpha)-19-Norpregn-4-en-20-yne-3,17-diol Diacetate
- [The diacetate salt form of ethynodiol, a semi-synthetic progestational hormone agonist. Ethynodiol diacetate binds to cytoplasmic progesterone receptors in the reproductive system and subsequently activates progesterone receptor mediated gene expression. As a result of the negative feedback mechanism, luteinizing hormone (LH) release is inhibited, which leads to an inhibition of ovulation and an alteration in the cervical mucus and endometrium. In addition, ethynodiol diacetate has weak oestrogenic and androgenic properties. ( NCI )] (UMLS (NCI) C0015117) =Steroid; Pharmacologic Substance ;
=Norpregnenes;
ETHYNODIOL =ETHYNODIOL DIACETATE 1 MG | - 73. beta antiadrenergic agent
- [drug that binds to but does not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists; adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrythmias, angina pectoris, glaucoma, migraine headaches, and anxiety. ( CSP )] (UMLS (CSP) C0178504) =Pharmacologic Substance ;
=adrenergic antagonist;
=atenolol;
ENALAPRIL;
1-((1-Methylethyl)amino)-3-(1-naphthalenyloxy)-2-propanol;
|
- 24. (3beta)-3-Hydroxy-lup-20(29)-en-28-oic Acid
- [A pentacyclic lupane-type triterpene derivative of betulin (isolated from the bark of Betula alba, the common white birch) with antiinflammatory, anti-HIV and antineoplastic activities. Betulinic acid induces apoptosis through induction of changes in mitochondrial membrane potential, production of reactive oxygen species, and opening of mitochondrial permeability transition pores, resulting in the release of mitochondrial apogenic factors, activation of caspases, and DNA fragmentation. Although originally thought to exhibit specific cytotoxicity against melanoma cells, this agent has been found to be cytotoxic against non-melanoma tumor cell types including neuroectodermal.and brain tumor cells. ( NCI )] (UMLS (NCI) C0053530) =Organic Chemical; Pharmacologic Substance ;
| - 74. beta barrel
- [ ] (UMLS (CSP) C0599216) =Amino Acid Sequence
|
- 25. (3beta)-Stigmast-5-en-3-ol
- (UMLS (NCI) C0106127) =Steroid; Pharmacologic Substance
| - 75. beta carotene/VIT-A
- (UMLS (NCI) C0281420) =Therapeutic or Preventive Procedure
|
- 26. (3beta,16beta,17alpha,18beta,20alpha)-11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic Acid Methyl Ester
- [alkaloid isolated from the root of Rauwolfia species, used as an antihypertensive and sedative. ( CSP )] (UMLS (NCI) C0035179) =Organic Chemical; Pharmacologic Substance =rauwolfia alkaloid;
tranquilizer;
[CV490] ANTIHYPERTENSIVES, OTHER;
=RESCINNAMINE;
DESERPIDINE;
RESERPINE 0.25 MG;
RESERPINE 0.1 MG;
RESERPINE 0.125 MG | - 76. Beta Catenin
- [Beta-catenin is an adherens junction protein. Adherens junctions (AJs; also called the zonula adherens) are critical for the establishment and maintenance of epithelial layers, such as those lining organ surfaces. AJs mediate adhesion between cells, communicate a signal that neighboring cells are present, and anchor the actin cytoskeleton. In serving these roles, AJs regulate normal cell growth and behavior. At several stages of embryogenesis, wound healing, and tumor cell metastasis, cells form and leave epithelia. This process, which involves the disruption and reestablishment of epithelial cell-cell contacts, may be regulated by the disassembly and assembly of AJs. AJs may also function in the transmission of the contact inhibition' signal, which instructs cells to stop dividing once an epithelial sheet is complete. (from OMIM) ( NCI )] (UMLS (NCI) C0105770) =Amino Acid, Peptide, or Protein; Biologically Active Substance
|
- 27. (3beta,20beta)-20-Carboxy-11-oxo-30-norolean-12-en-3-yl-2-O-beta-D-glucopyranuronosyl-alpha-D-glucopyranosiduronic Acid
- [A widely used anti-inflammatory agent isolated from the licorice root. It is metabolized to GLYCYRRHETINIC ACID, which inhibits 11-BETA-HYDROXYSTEROID DEHYDROGENASES and other enzymes involved in the metabolism of CORTICOSTEROIDS. Therefore, glycyrrhizic acid, which is the main and sweet component of licorice, has been investigated for its ability to cause hypermineralocorticoidism with sodium retention and potassium loss, edema, increased blood pressure, as well as depression of the renin-angiotensin-aldosterone system. ( MSH )] (UMLS (NCI) C0061751) =Organic Chemical; Pharmacologic Substance ;
| - 77. beta caveolin
- [ ] (UMLS (CSP) C0287873) =Amino Acid, Peptide, or Protein; Receptor
|
- 28. (3beta,20beta)-3-(3-Carboxy-1-oxopropoxy)-11-oxoolean-12-en-29-oic Acid
- [An agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise the drug is low in toxicity. ( MSH )] (UMLS (NCI) C0006979) =Steroid; Pharmacologic Substance
| - 78. Beta Cell
- [A cell that composes the bulk of the islets of Langerhans and secretes insulin. ( NCI )] (UMLS (NCI) C0030281) =Cell ;
|
- 29. (3beta,20beta)-3-Hydroxy-11-oxoolean-12-en-29-oic Acid
- [An oleanolic acid from GLYCYRRHIZA that has some antiallergic, antibacterial, and antiviral properties. It is used topically for allergic or infectious skin inflammation and orally for its aldosterone effects in electrolyte regulation. ( MSH )] (UMLS (NCI) C0017986) =Organic Chemical; Pharmacologic Substance
| - 79. Beta Cell Neoplasm
- [A usually benign, well circumscribed neoplasm arising from the beta cells of the pancreas. Patients exhibit symptoms related to hypoglycemia due to inappropriate secretion of insulin. ( NCI )] (UMLS (NCI) C0021670) =Neoplastic Process =Islet Cell Adenoma;
|
- 30. (3beta,5beta)-3-[(O-2,6-Dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-O-2,6-dideoxy-beta-D-ribo-hexopyranosyl-(1-4)-2,6-dideoxy-beta-D-ribo-hexopyranosyl)oxy]-14-hydroxycard-20(22)-enolide
- [A lipid soluble cardiac glycoside that inhibits the plasma membrane sodium potassium ATPase, leading to increased intracellular sodium and calcium levels and decreased intracellular potassium levels. In studies increased intracellular calcium precedes cell death and decreased intracellular potassium increase caspase activation and DNA fragmentation, causing apoptosis and inhibition of cancer cell growth. (NCI) ( NCI )] (UMLS (NCI) C0012258) =Steroid; Carbohydrate; Pharmacologic Substance; Biologically Active Substance =cardenolide;
[CV050] DIGITALIS GLYCOSIDES | - 80. Beta Cellulin
- [Betacellulin is a member of the EGF family of growth factors; a potent mitogen for retinal pigment epithelia and vascular smooth muscle cells. Betacellulin effects may be mediated by the EGF receptor and/or related receptors. The precursor form is a type I membrane protein that contains one EGF-like domain and is synthesized in several tissues and tumor cells. Betacellulin from pancreatic beta cells could play a role in the vascular complications associated with diabetes. (from Swiss-Prot P35070 and NCI) ( NCI )] (UMLS (NCI) C0213553) =Amino Acid, Peptide, or Protein; Biologically Active Substance
|
- 31. (3beta,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
- [produced in human and other animal tissue by photoactivation (normally sunlight on skin) of 7-dehydrocholesterol. ( CSP )] (UMLS (NCI) C0008318) =Steroid; Pharmacologic Substance; Vitamin =Cholestenes;
Secosteroids;
sterol;
[VT500] VITAMIN D;
[VT509] VITAMIN D, OTHER;
TO BE DELETED INGREDIENT PREPARATIONS =Hydroxycholecalciferols;
CHOLECALCIFEROL/FISH LIVER OIL OINT,TOP;
CRITICARE HN LIQUID;
THICKENUP POWDER;
ULTRACAL TUBE-FEEDING LIQUID;
CHOLECALCIFEROL 133 UNT;
CHOLECALCIFEROL 400 IU;
CHOLECALCIFEROL 400 UNT/ML;
| - 81. Beta Chemokine
- [Encoded by CC Cytokine Genes, Beta Chemokines are CC-type dual-cysteine chemokines with adjacent cysteine residues in their primary sequence that act as chemoattractants for lymphocytes, monocytes, eosinophils, and basophils, but not for neutrophils. (NCI) ( NCI )] (UMLS (NCI) C0282552) =Amino Acid, Peptide, or Protein; Immunologic Factor
|
- 32. (9beta,10alpha)-17-(Acetyloxy)-6-methylpregna-4,6-diene-3,20-dione
- [The acetate salt form of megestrol, a synthetic derivative of the naturally occurring female sex hormone progesterone with potential anti-estrogenic and antineoplastic activity. Mimicking the action of progesterone, megestrol acetate binds to and activates nuclear progesterone receptors in the reproductive system, and causes the ligand-receptor complex to be translocated to the nucleus where it binds to and promotes expression of target genes. This leads to an alteration in protein synthesis, which modulates cell growth of reproductive tissues. Due to the negative feedback mechanism seen with progesterone, megestrol also blocks luteinizing hormone (LH) release from the pituitary gland, thereby leading to an inhibition of ovulation and an alteration in the cervical mucus and endometrium. Furthermore, without stimulation of LH, estrogen release from the ovaries is stopped, hence impedes the growth of estrogen-sensitive tumor cells. ( NCI )] (UMLS (NCI) C0065879) =Steroid; Pharmacologic Substance; Hormone =MEG;
=Megestrol 20 MG;
MEGESTROL ACETATE 200 MG/5ML;
MEGESTROL ACETATE 40 MG;
| - 82. Beta Chemokine Exodus-1
- [Repressed by IL-10 and induced by LPS, PMA, TNF, and INF Gamma in liver, lymph nodes, appendix, PBL, thymus, prostate, testis, small intestine, colon, and fetal lung, the human CCL20 Gene product (Intercrine Beta Family), Small Inducible Cytokine A20, is a secreted chemotactic factor for lymphocytes, neutrophils, and dendritic cells that binds CCR6 and may inhibit proliferation of myeloid progenitors. (NCI) ( NCI )] (UMLS (NCI) C1308247) CC Chemokine LARC;
CCL20;
Chemokine (C-C Motif) Ligand 20;
Exodus-1;
Liver and Activation-Regulated Chemokine;
Macrophage Inflammatory Protein 3 Alpha;
MIP-3-Alpha;
Small Inducible Cytokine A20;
Small Inducible Cytokine Subfamily A (Cys-Cys), Member 20 =Amino Acid, Peptide, or Protein; Immunologic Factor |
- 33. (betaR,deltaR)-2-(4-Fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid
- [a synthetic lipid-lowering agent; an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase that catalyzes the conversion of HMG-CoA to mevalonate, an early and rate-limiting step in cholesterol biosynthesis. ( CSP )] (UMLS (NCI) C0286651) =Organic Chemical; Pharmacologic Substance =antihypercholesterolemic agent;
[CV350] ANTILIPEMIC AGENTS;
Heptanoic Acids;
pyrrole =Atorvastatin Calcium | - 83. Beta Chemokine Exodus-3
- [Expressed in lymph nodes, thymus, appendix, colon, trachea, spleen, small intestine, lung, kidney, and stomach by human CCL19 Gene (Intercrine Beta Family), secreted immunoregulatory 98-aa 11-kD (precursor) Small Inducible Cytokine A19 is involved in inflammatory and immunological responses, binds to CCR7 receptor, and plays a role in thymic T cell trafficking and T and B cell migration. (NCI) ( NCI )] (UMLS (NCI) C0539791) =Amino Acid, Peptide, or Protein; Immunologic Factor ;
|
- 34. .beta.,.beta.'-Dichlorodiethylaniline
- [An alkylating mustard with antineoplastic activity. Aniline mustard forms covalent linkages with nucleophilic centers, resulting in depurination, base miscoding and strand scission, and crosslinking of DNA strands, all of which contribute to its cytotoxicity. (NCI04) ( NCI )] (UMLS (NCI) C0003040) =Organic Chemical; Pharmacologic Substance
| - 84. Beta Chemokine Receptor-Like 1
- [Up-regulated by chronic inflammation and encoded by human CX3CR1 Gene (CCR Family, Rhodopsin Family), 355-amino acid 40.4-kD high-affinity Fractalkine Receptor is a seven transmembrane protein expressed in brain, peripheral blood leukocytes, and spleen as a regulator of leukocyte endothelial trafficking: chemotaxis, cell migration, and adhesion. CX3CR1 signals through a pertussis toxin sensitive G-protein to induce migration and contains common GPCR features. Tyrosine sulfation enhances fractalkine-induced cell adhesion. Sharing the CX3C motif, RSV G glycoprotein can use CX3CR1 as a receptor. CX3CR1 may be an HIV envelope protein co-receptor with CD4. Homozygous CX3CR1 I249/M280 haplotype enhances infection and progression to AIDS. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )] (UMLS (NCI) C1143767) Chemokine (C-C) Receptor-Like 1;
Chemokine (C-X3-C Motif) Receptor 1;
Chemokine, CX3C Motif, Receptor 1;
CMKBLR1;
CMK-BRL-1;
CX3C Chemokine Receptor 1;
C-X3-C CKR-1;
CX3CR1;
CX3CR1 Protein;
Fractalkine Receptor;
Fractalkine Receptor CX3CR1;
G Protein-Coupled Receptor 13;
G Protein-Coupled Receptor V28;
G-Protein Coupled Receptor Family 1 =Amino Acid, Peptide, or Protein; Receptor ;
|
- 35. .beta.,.beta.-Dimethylcysteine
- [beta dimethyl analog of cysteine; USP lists as a chelating agent. ( CSP )] (UMLS (NCI) C0030817) =Amino Acid, Peptide, or Protein; Pharmacologic Substance =Amino Acids, Sulfur;
[MS100] ANTIRHEUMATICS;
chelating agent;
.beta.,.beta.-Dimethylcysteine =PENICILLAMINE 125 MG;
PENICILLAMINE 250 MG;
.beta.,.beta.-Dimethylcysteine;
| - 85. beta counter
- [ ] (UMLS (CSP) C0599391) =Medical Device ;
|
- 36. .beta.-2'-Deoxy-6-thioguanosine
- [A thiopurine nucleoside derivative with antineoplastic activity. After conversion to the triphosphate, beta-thioguanine deoxyriboside is incorporated into DNA, resulting in inhibition of DNA replication. This agent is cytotoxic against leukemia cell lines and has demonstrated some activity against leukemia cells in vivo. Beta-thioguanine deoxyriboside demonstrates antineoplastic activity against 6-thioguanine-resistant tumor cells. (NCI04) ( NCI )] (UMLS (NCI) C0053376) =Organic Chemical; Pharmacologic Substance; Biologically Active Substance
| - 86. Beta DNA polymerase
- [Human DNA polymerase beta protein (334 aa 38 kDa) is encoded by the human DNA polymerase beta (POLB) gene. This monomer protein is a DNA repair enzyme that catalyzes "gap-filling" DNA synthesis in a stepwise, distributive manner during base excision repair. This enzyme is required for DNA maintenance, replication, recombination, and drug resistance. ( NCI )] (UMLS (NCI) C0525039) =Amino Acid, Peptide, or Protein; Enzyme
|
- 37. .beta.-Carotene
- [A vitamin A precursor. Beta carotene belongs to the family of fat-soluble vitamins called carotenoids. ( NCI )] (UMLS (NCI) C0053396) =Organic Chemical; Pharmacologic Substance; Vitamin =carotene;
[VT050] VITAMIN A;
TO BE DELETED INGREDIENT PREPARATIONS;
=VITAMIN A (AS ACETATE & BETA CAROTENE);
VITAMIN A (AS PALMITATE & BETA CAROTENE);
BETA CAROTENE 0.25 MG/240ML;
BETA CAROTENE 1.06 MG/L;
BETA CAROTENE 400 UNT;
BETA CAROTENE 6000 UNT;
Beta Carotene 25000 UNT;
Beta Carotene 1000 UNT;
Beta Carotene 50 MG;
Beta Carotene 10000 UNT;
Beta Carotene 30 MG;
Beta Carotene 25 MG | - 87. Beta Endorphin
- [A neuropeptide that mediates pain perception. ( NCI )] (UMLS (NCI) C0005210) =Amino Acid, Peptide, or Protein; Neuroreactive Substance or Biogenic Amine ;
|
- 38. .beta.-Cytosine arabinoside
- [class of pyrimidine nucleoside analogs used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia; antimetabolite antineoplastic agents that inhibit the synthesis of DNA with actions specific for the S phase of the cell cycle; also have antiviral and immunosuppressant properties. ( CSP )] (UMLS (NCI) C0010711) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=[AN300] ANTINEOPLASTICS, ANTIMETABOLITES;
arabinonucleoside;
cytidine;
cytosine nucleoside =1,3, 5-Triazin-2(1H)-one, 4-amino-1-.beta.-D- arabinofuranosyl- (9CI);
Cytarabine Liposome;
CYTARABINE 2 GM/VIL;
CYTARABINE 1 GM/VIL;
CYTARABINE 100 MG;
CYTARABINE 500 MG;
| - 88. beta fructofuranosidase
- [A glycoside hydrolase found primarily in PLANTS and YEASTS. It has specificity for beta-D-fructofuranosides such as SUCROSE. ( MSH )] (UMLS (CSP) C0053409) =Amino Acid, Peptide, or Protein; Enzyme ;
=O glycosidase;
|
- 39. .beta.-Pyrazomycin
- [A nucleoside analog. Pyrazofurin potently inhibits orotidine 5'-monophosphate (OMP) decarboxylase, thereby interfering with de novo synthesis of uridine nucleotides and resulting in cytotoxicity. This agent also causes a rapid depletion of the pyrimidine deoxynucleotide pool, thereby inhibiting DNA synthesis and cell replication. (NCI04) ( NCI )] (UMLS (NCI) C0072661) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
| - 89. beta galactocerebrosidase deficiency
- [inherited, demyelinating, human lipid storage disease caused by a deficiency of galactosylceramidase; manifestations include convulsions, quadriplegia, blindness, deafness, and mental retardation. ( CSP )] (UMLS (CSP) C0023521) =Disease or Syndrome ;
=LEUKODYSTROPHY;
Sphingolipidoses;
inborn lysosomal enzyme disorder;
enzyme deficiency;
Hereditary Central Nervous System Demyelinating Diseases;
|
- 40. 1-(2-(beta-naphthyloxy)ethyl)-3-methyl-2-pyrazolin-5-one
- [A pyrazolinone derivative with potential antimetastatic activities. Nafazatrom, originally developed as an antithrombotic agent, inhibits the key prostaglandin catabolic enzyme, 15-hydroxyprostaglandin dehydrogenase, thereby prolonging the biological half-life of prostacyclin (prostaglandin I2; PGI2) and preventing intravascular coagulation. This agent also serves as a reducing cofactor with the hydroperoxidase moiety of cyclooxygenase and accelerates the conversion of arachidonic acid into precursors of PGI2. Elevated level of PGI2 prevents aggregation of platelets and subsequently, decreases the formation of tumor cell-platelet aggregates as well as their sequestration in blood vessels, which is an important initiating step in the development of metastasis. ( NCI )] (UMLS (NCI) C0053025) =Organic Chemical; Pharmacologic Substance
| - 90. beta galactosidase
- [A group of enzymes that catalyzes the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-galactosides. Deficiency of beta-Galactosidase A1 may cause GANGLIOSIDOSIS, GM1. ( MSH )] (UMLS (CSP) C0005220) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Enzyme
|
- 41. 1-.beta.-D-Ribofuranosyl-1H-1,2, 4-triazole-3-carboxamide
- [1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamid e; antiretroviral agent with potential efficacy against AIDS. ( CSP )] (UMLS (NCI) C0035525) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=[AM800] ANTIVIRALS;
ribonucleoside;
Reverse Transcriptase Inhibitor;
nucleoside analog =RIBAVIRIN 200 MG;
RIBAVIRIN 42 X 200 MG;
RIBAVIRIN 70 X 200 MG;
RIBAVIRIN 84 X 200 MG;
RIBAVIRIN 6;
| - 91. beta galactosidase deficiency
- [form of gangliosidosis characterized by accumulation of G(M1) ganglioside and oligosaccharides in lysosomes caused by an absence or severe deficiency of the enzyme beta-galactosidase (type A1); three phenotypes of this disorder are infantile (generalized), juvenile, and adult; the infantile form is characterized by skeletal abnormalities, hypotonia, poor psychomotor development, hirsutism, hepatosplenomegaly, and facial abnormalities; the juvenile form features hyperacusis, seizures, and psychomotor retardation; the adult form features progressive intellectual deterioration, involuntary movements, ataxia, and spasticity. ( CSP )] (UMLS (CSP) C0085131) =Disease or Syndrome ;
=Gangliosidoses;
enzyme deficiency |
- 42. 1-beta-D-Ribofuranosyl-2(1H)-pyrimidinone
- [A synthetic cytidine analogue and a cytidine deaminase inhibitor with anticancer activity. Following metabolic activation by phosphorylation and incorporation into DNA, zebularine inhibits DNA methyltransferase through covalent complex formation between the enzyme and zebularine-substituted DNA, hence resulting in non-specific, genome-wide induction of demethylation including the removal of aberrant methylation of promoter regions of genes critical for normal cellular functions. ( NCI )] (UMLS (NCI) C0084253) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
| - 92. beta globin
- [ ] (UMLS (CSP) C0005221) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 43. 11-beta,17-alpha,21-Trihydroxy-4-pregnene-3,20-dione 17-alpha-butyrate
- [The butyrate salt form of hydrocortisone, a synthetic glucocorticoid receptor agonist with antiinflammatory, antipruritic and vasoconstrictive effects. Binding and activation of the glucocorticoid receptor results in the activation of lipocortin that in turn inhibits cytosolic phospholipase A2. Lack of phospholipase A2 prevents the release of arachidonic acid, precursor for inflammatory mediator prostaglandins and leukotrienes, from the cell membrane. Secondly, mitogen-activated protein kinase (MAPK) phosphatase 1 is induced, thereby leading to dephosphorylation and inactivation of Jun N-terminal kinase directly inhibiting c-Jun mediated transcription. Finally, transcriptional activity of nuclear factor (NF)-kappa-B is blocked, thereby inhibits the transcription of cyclooxygenase 2, which is essential for prostaglandin production. ( NCI )] (UMLS (NCI) C0352536) =Steroid; Pharmacologic Substance =(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione;
=HYDROCORTISONE BUTYRATE 0.1 % | - 93. beta globulin
- [group of serum proteins with an electrophoretic mobility that falls between alpha globulins and gamma globulins. ( CSP )] (UMLS (CSP) C0005157) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 44. 11-beta-Hydroxy-6-alpha-methylpregn-4-ene-3,20-dione
- [A topical, synthetic glucocorticoid with metabolic, anti-inflammatory and anti-allergic properties. Medrysone exerts its effect by interacting with specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. This results in an induction of the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions is accomplished. ( NCI )] (UMLS (NCI) C0065865) =Steroid; Pharmacologic Substance ;
=Pregnenediones;
[OP300] ANTI-INFLAMMATORIES, TOPICAL OPHTHALMIC =MEDRYSONE 1 %;
| - 94. beta glucosidase
- [An exocellulase with specificity for a variety of beta-D-glycoside substrates. It catalyzes the hydrolysis of terminal non-reducing residues in beta-D-glucosides with release of GLUCOSE. ( MSH )] (UMLS (CSP) C0005223) =Amino Acid, Peptide, or Protein; Enzyme ;
|
- 45. 11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione 21-Acetate
- [The acetate salt of a synthetic glucocorticoid receptor agonist with immunosuppressive and antiinflammatory effects. Methylprednisolone acetate is converted into active prednisolone in the body, which activates glucocorticoid receptor mediated gene expression. This includes inducing synthesis of anti-inflammatory protein IkappaB-alpha and inhibiting synthesis of nuclear factor kappaB (NF-kappaB). As a result, proinflammatory cytokine production such as IL-1, IL-2 and IL-6 is down-regulated and cytotoxic T-lymphocyte activation is inhibited. Therefore, an overall reduction in chronic inflammation and autoimmune reactions may be achieved. ( NCI )] (UMLS (NCI) C0600901) =Steroid; Pharmacologic Substance ;
=(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione;
[DE200] ANTI-INFLAMMATORY, TOPICAL;
[RS100] ANTI-INFLAMMATORIES, RECTAL;
Unclassified Ingredients =METHYLPREDNISOLONE ACETATE 40 MG/ML;
METHYLPREDNISOLONE ACETATE 0.25 %;
METHYLPREDNISOLONE ACETATE 1 %;
METHYLPREDNISOLONE ACETATE 10 MG;
METHYLPREDNISOLONE ACETATE 20 MG/ML;
METHYLPREDNISOLONE ACETATE 80 MG/ML;
METHYLPREDNISOLONEACETATE 0.25 % | - 95. beta glucuronidase
- [ ] (UMLS (CSP) C0017776) =Amino Acid, Peptide, or Protein; Enzyme; Indicator, Reagent, or Diagnostic Aid =O glycosidase;
|
- 46. 11beta,17,21-Trihydroxypregn-4-ene-3,20-dione 17-Valerate
- [The valerate salt form of hydrocortisone, a synthetic glucocorticoid receptor agonist with antiinflammatory, antipruritic and vasoconstrictive effects. Binding and activation of the glucocorticoid receptor results in the activation of lipocortin that in turn inhibits cytosolic phospholipase A2. Lack of phospholipase A2 prevents the release of arachidonic acid, precursor for inflammatory mediator prostaglandins and leukotrienes, from the cell membrane. Secondly, mitogen-activated protein kinase (MAPK) phosphatase 1 is induced, thereby leads to dephosphorylation and inactivation of Jun N-terminal kinase directly inhibiting c-Jun mediated transcription. Finally, transcriptional activity of nuclear factor (NF)-kappa-B is blocked, thereby inhibits the transcription of cyclooxygenase 2, which is essential for prostaglandin production. ( NCI )] (UMLS (NCI) C0063079) =Steroid; Pharmacologic Substance ;
=(11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione;
=HYDROCORTISONE VALERATE 0.2 % | - 96. beta heparin
- [naturally occurring glycosaminoglycan found mostly in the skin and in connective tissue, differs from chondroitin sulfate A by containing iduronic acid in place of glucuronic acid, its epimer, at carbon atom 5. ( CSP )] (UMLS (CSP) C0011602) =Carbohydrate; Biologically Active Substance =chondroitin;
chondroitin sulfate =danaparoid;
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- 47. 17 Beta-hydroxy-2 alpha-methyl-5 alpha-androstan-3-one
- (UMLS (NCI) C0960041) 2 Alpha-5 alpha-17 beta-17-hydroxy-2-methyl-androstan-3-one;
2 Alpha-methylandrostan-17 beta-ol-3-one;
2 Alpha-methyldihydrotestosterone;
2.alpha.-Methyldihydrotestosterone;
5.alpha.-Androstan-3-one, 17.beta.-hydroxy-2.alpha.-methyl- =Steroid; Pharmacologic Substance | - 97. beta hydroxybutyrate
- [butyric acid substituted in the beta or 3 position; one of the ketone bodies produced in the liver and occurs at high levels in the blood and urine in ketosis. ( CSP )] (UMLS (CSP) C0106006) =Organic Chemical; Biologically Active Substance =butyrate;
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- 48. 17 Beta-Hydroxysteroid Dehydrogenase Type 7
- [Encoded by human HSD17B7 Gene (SDR Family) and expressed in breast, ovaries, pregnant uterus, placenta, testis, thymus, prostate, fetal liver, and some neural tissues, 341-amino acid 38-kD 17-Beta-Hydroxysteroid Dehydrogenase 7 oxidizes or reduces estrogens and androgens. Responsible for biosynthesis of estradiol in the corpus luteum during pregnancy, the membrane-associated phosphorylated enzyme is nearly 75% identical to rodent proteins and contains a short chain dehydrogenase domain. Close to the transmembrane domain, HSD17B7 contains a 28-residue superficial loop: a candidate prolactin receptor (PRLR)-binding domain. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )] (UMLS (NCI) C1334066) 17 Beta-Hydroxysteroid Dehydrogenase Type VII;
17-Beta-HSD 7;
17-Beta-Hydroxysteroid Dehydrogenase 7;
EC 1.1.1.51;
Estradiol 17 Beta-Dehydrogenase 7;
HSD17B7;
Hydroxysteroid (17-Beta) Dehydrogenase 7 =Amino Acid, Peptide, or Protein; Enzyme | - 98. beta hydroxybutyrate dehydrogenase
- [ ] (UMLS (CSP) C0020331) =Amino Acid, Peptide, or Protein; Enzyme ;
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- 49. 17 Beta-OH-7 beta, 17 alpha-dimethyl-androst-4-ene-3-one
- [A 17-alkylated orally active androgenic steroid. Calusterone may alter the metabolism of estradiol and reduce estrogen production. (NCI04) ( NCI )] (UMLS (NCI) C0006790) =Steroid; Pharmacologic Substance
| - 99. Beta IGH3
- [Constitutively expressed by human TGFBI Gene in many tissues (high in corneal epithelium) and TGF-beta induced, highly conserved 683-aa 75-kDa (precursor) extracellular Transforming Growth Factor-Beta Induced Protein IGH3 contains an N-signal peptide, four 140-aa FAS1 domains with internal homology, and a C-RGD motif. RGD is found in many extracellular matrix proteins that modulate cell adhesion and serves as a ligand recognition sequence for several integrins. With similar structure to fasciclin I (putative neuronal cell adhesion protein) and OSF-2 (potential bone adhesion protein), TGFBI binds to types I, II, and IV collagens. A potential adhesion protein, TGFBI may play role in cell-collagen interactions, may be associated with microfibrils and the cell surface, and may be involved in endochondral bone formation. TGFBI defects cause CDGG1, CDRB, CDL1, CDL3A, and ACD. (NCI) ( NCI )] (UMLS (NCI) C0172642) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
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- 50. 17-Beta Hydroxysteroid Dehydrogenase
- [Expressed in many peripheral tissues (high in placenta) by human HSD17B2 Gene (SDR Family), 387-aa 43-kDa Hydroxysteroid 17-Beta Dehydrogenase 2 is a potential type II membrane protein enzyme with an N-terminal type II signal-anchor motif and a C-terminal ER retention motif, likely associated with ER membranes, that uses NADH in the oxidative inactivation metabolism of testosterone and androstenedione, as well as estradiol and estrone. HSD17B2 also has 3-beta-HSD activity and 20-alpha-HSD activity toward 20-alpha-dihydroprogesterone. (NCI) ( NCI )] (UMLS (NCI) C0014914) =Amino Acid, Peptide, or Protein; Enzyme ;
| - 100. Beta Interferon
- [major interferon produced by double stranded RNA induced fibroblast cultures; the primary producer cells are fibroblasts, epithelial cells and macrophages, and the major activity is antiviral. ( CSP )] (UMLS (NCI) C0015980) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor =Interferon Type I;
IFN =interferon beta 1b;
interferon beta 1a;
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