[The acetate salt form of cortisone, a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with anti-inflammatory and immunomodulating properties. Cortisone acetate diffuses through the cell membrane and binds to nuclear glucocorticoid receptors. The receptor-ligand complex binds to promotor regions of certain genes and initiates RNA transcription. This results in an induction of synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. ( NCI )]
UMLS (NCI) C0056391 - Steroid
- Pharmacologic Substance
- Hormone
Relation/PAR: 17,21-Dihydroxypregn-4-ene-3,11,20-trione
Relation/CHD: CORTISONE ACETATE 25 MG
CORTISONE ACETATE 50 MG/ML
CORTISONE ACETATE 5 MG
CORTISONE ACETATE 10 MG