[An orally administered third generation platinum compound with potential antineoplastic activity. Satraplatin forms highly reactive, charged, platinum complexes which bind to nucleophilic groups in DNA, inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links. These cross-links result in cell growth inhibition and apoptosis. ( NCI )]
UMLS (NCI) C1142934(OC-6-43)-bis(acetato-O)amminedichloro(cyclohexanamine)platinum
platinum,bis(acetato-O)amminedichloro(cyclohexanamine)-,(OC-6-43)
Satraplatin
- Organic Chemical
- Pharmacologic Substance