[An acylated sulfhydryl-containing derivative of glycine with reducing and complexing properties. Tiopronin breaks the disulphide bond of cystine and binds the sulfhydryl group of the resultant cysteine monomers to form a soluble tiopronin-cysteine-mixed disulfide, which is more water-soluble than cystine and is readily excreted. This leads to a reduction in urinary cystine concentration and subsequently reduces cystine stone formation. ( NCI )]
UMLS (NCI) C0025405 - Amino Acid, Peptide, or Protein
- Pharmacologic Substance
Relation/PAR: Amino Acids, Sulfur
GLYCINE
Unclassified Ingredient Preparations
Relation/CHD: Thiopronine 100 MG