(+-)-Verapamil hydrochloride

[The hydrochloride form of Verapamil, which is a phenylalkylamine calcium channel blocking agent. Verapamil inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and decreasing myocardial contractility. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in some multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents. (NCI04) ( NCI )]

UMLS (NCI) C0700468

Organic Chemical
Pharmacologic Substance

Relation/PAR: alpha-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-alpha-(1-methylethyl)benzeneacetonitrile

Relation/CHD: VERAPAMIL HYDROCHLORIDE 120 MG
VERAPAMIL HYDROCHLORIDE 180 MG
VERAPAMIL HYDROCHLORIDE 240 MG
VERAPAMIL HYDROCHLORIDE 40 MG
VERAPAMIL HYDROCHLORIDE 80 MG
VERAPAMIL HYDROCHLORIDE 2.5 MG/ML
VERAPAMIL HYDROCHLORIDE 360 MG
VERAPAMIL HYDROCHLORIDE 200 MG
VERAPAMIL HYDROCHLORIDE 100 MG

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