UMLS - Terms starting with ‘B’

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2,2-bis(Bromomethyl)-1,3-Propanediol: [A solid, white, organo-halide carcinogen with a musty odor that consists for 78% of 2,2-Bis(Bromomethyl)-1,3-Propanediol. BBMP is used in industry as a flame retardant in unsaturated polyester resins, in molded products and in rigid polyurethane foam. BBMP is mutagenic and carcinogenic in animals and is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0045288) =Organic Chemical; Hazardous or Poisonous Substance ;;
2,3-Benzfluoranthene: [A colorless, aromatic hydrocarbon consisting of five fused rings and formed by the incomplete burning of organic matter. Benzo(b)fluoranthene is primarily found in gasoline exhaust, tobacco and cigarette smoke, coal tar, soot, amino acids and fatty acid pyrolysis products. This substance is used only for research purposes. Benzo(b)fluoranthene is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0053199) =Organic Chemical; Hazardous or Poisonous Substance ;;
2,6-Bis(1,1-dimethylethyl)-4-methylphenol: [2,6-di-tert-butyl-4-methylphonol, a perservative commonly used in packaged foods. ( CSP )] (UMLS (NCI) C0006507) =Organic Chemical; Pharmacologic Substance =Cresols;;food additive;;phenol;;Unclassified Ingredient Preparations =AQUA-A CREAM;;AQUADERM CREAM;;AQUADERM LOTION;;ALPHA KERI BAR SOAP;;KERI FACIAL SOAP;;BUTYLATED HYDROXYTOLUENE 100 GM
2-(4-Bromophenyl)-4H-1-benzopyran-4-one: (UMLS (NCI) C0763460) 2-(4-Bromophenyl)chromen-4-one;;4'-Bromoflavone;;4-Bromoflavone =Organic Chemical; Pharmacologic Substance
2-.beta.-D-Ribofuranosyl-4-thiazolecarboxamide: (UMLS (NCI) C0092663) =Organic Chemical; Pharmacologic Substance
2-Benzimidazolinebutryric acid, 1-methyl-5-bis(2-chloroethyl)amino-, hydrochloride: [The hydrochloride salt of bendamustine, a novel alkylating agent of the nitrogen mustard family with antitumor activity. Bendamustine, chemically related to the alkylator chlorambucil, has three active moieties: an alkylating group, in common with the nitrogen mustard family; a benzimidazole ring, which may act as a purine analog; and a butyric acid side-chain. This agent undergoes extensive first-pass metabolism by cytochrome p450 enzymes in vivo. One of the hydroxy metabolites, beta-hydroxybendamustine, alkylates and crosslinks macromolecules, thereby resulting in DNA, RNA and protein synthesis inhibition, and subsequently inducing apoptosis. ( NCI )] (UMLS (NCI) C0772139) Bendamustin Hydrochloride;;Bendamustine Hydrochloride =Organic Chemical; Pharmacologic Substance ;;
2-benzofurancarboximide,N-(2-((1-(chloromethyl)-1,6-dihydro-8-methyl-5-(((phenylamino)carbonyl0oxy0benzo(1,2-b:4,3-b')dipyrrol-3(2H0-yl)carbonyl-1H-indol-5-yl)-6-(diethylamino)-,(S): [An anticancer drug that belongs to the family of drugs called alkylating agents. ( NCI )] (UMLS (NCI) C0172048) =Organic Chemical; Pharmacologic Substance ;;
2-bis[Cyclo(N-methyl-L-valyl-sarcosyl-L-prolyl-D-valyl-L-threonyl)]-1,9 dimethyl-4,6 3H-phenoxazinone-3: [An anticancer drug that belongs to the family of drugs called antitumor antibiotics. ( NCI )] (UMLS (NCI) C0010934) =Amino Acid, Peptide, or Protein; Antibiotic =antineoplastic antibiotics;;Heterocyclic Compounds, 3-Ring;;cyclic peptide;; =DACTINOMYCIN 0.5 MG;;
2-Bromo-alpha-ergocryptine: [D2 dopamine agonist used as a prolactin inhibitor. ( CSP )] (UMLS (NCI) C0006230) =Organic Chemical; Pharmacologic Substance ;; =[CN500] ANTIPARKINSON AGENTS;;ergoline;;Dopamine Agonist;;[AU900] AUTONOMIC AGENTS, OTHER =2-Bromo-alpha-ergocryptine Mesylate
2-Bromo-alpha-ergocryptine Mesylate: [The mesylate salt form of bromocriptine, a semisynthetic, ergot alkaloid with antiparkinson and lactation inhibitory activity. Bromocriptine selectively binds to and activates the postsynaptic dopamine D2-like receptors in the corpus striatum of the central nervous system (CNS). D2-like receptors are coupled to inhibitory G-proteins, which inhibit adenylyl cyclase, thereby preventing signal transduction mediated via cAMP and leading to an inhibitory effect on neurotransmission. This improves Parkinson symptoms, such as dyskinesia. Bromocriptine also has an inhibitory effect on the anterior pituitary gland, which results in blockage of prolactin secretion, thereby suppressing lactation. ( NCI )] (UMLS (NCI) C0546852) =Organic Chemical; Pharmacologic Substance =2-Bromo-alpha-ergocryptine;; =BROMOCRIPTINE MESYLATE 2.5 MG;;BROMOCRIPTINE MESYLATE 5 MG
2-Butenoic acid, 3-bromo-4-(4-methoxyphenyl)-4-oxo-, sodium salt, (Z)- (9CI): (UMLS (NCI) C0893303) Acrylic acid, 3-p-anisoyl-3-bromo-, sodium salt;;Sodium Bromebrate;;Sodium cis-Beta-4-methoxybenzoyl-beta-bromacrylate =Organic Chemical; Pharmacologic Substance
2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol: [antihypertensive agent; nonpeptide angiotension 1 subtype; angiotension 2 receptor antagonist/inhibitor. ( CSP )] (UMLS (NCI) C0126174) =Organic Chemical; Pharmacologic Substance ;; =antihypertensive agent;;biphenyl compound;;imidazole;;Tetrazoles;;[CV805] ANGIOTENSIN II INHIBITORS;; =2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol, Monopotassium Salt;;LOSARTAN 25 MG;;LOSARTAN 50 MG
2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol, Monopotassium Salt: [The potassium salt form of losartan, a non-peptide angiotensin II antagonist with antihypertensive activity. Losartan potassium selectively and competitively blocks the binding of angiotensin II to the angiotensin I (AT1) receptor. Angiotensin II, formed from angiotensin I by angiotensin-converting enzyme (ACE), stimulates the adrenal cortex to synthesize and secrete aldosterone, which decreases the excretion of sodium and increases the excretion of potassium. Angiotensin II also acts as a vasoconstrictor in vascular smooth muscle. Losartan potassium, by blocking the binding of angiotensin II to the AT 1 receptor, promotes vasodilatation and decreases the effects of aldosterone. ( NCI )] (UMLS (NCI) C0700492) =Organic Chemical; Pharmacologic Substance ;; =2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol;; =LOSARTAN POTASSIUM 25 MG;;LOSARTAN POTASSIUM 50 MG;;LOSARTAN POTASSIUM 100 MG;;
2-[bis(2-chloroethyl)amino]-3-(2-chloroethyl)tetrahydro-2H-1,3,2-oxaphosphorine 2-oxide: [An orally bioavailable oxazaphosphorine prodrug with antineoplastic activity. Trofosfamide (TFF) is metabolized predominantly to the cyclophosphamide analogue ifosfamide (IFO), which is then metabolized by liver cytochrome P450s to the active isophosphoramide mustard (IPM). IPM alkylates DNA to form DNA-DNA cross-links, which may result in inhibition of DNA, RNA and protein synthesis, and ultimately lead to tumor cell apoptosis. ( NCI )] (UMLS (NCI) C0077375) =Organic Chemical; Pharmacologic Substance ;;
2-[bis(2-chloroethyl)amino]-4-hydroperoxytetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide: [The active metabolite of the nitrogen mustard cyclophosphamide with potent antineoplastic and immunosuppressive properties. Perfosfamide alkylates DNA, thereby inhibiting DNA replication and RNA and protein synthesis. (NCI04) ( NCI )] (UMLS (NCI) C0163054) =Organophosphorus Compound; Pharmacologic Substance ;;
20-29% BDY BRN/10-19% 3D: [ ] (UMLS (ICD9CM) C0161334) =Injury or Poisoning
20-29% BDY BRN/20-29% 3D: [ ] (UMLS (ICD9CM) C0161335) =Injury or Poisoning
20-29% BDY BRN/3 DEG NOS: [ ] (UMLS (ICD9CM) C0161333) =Injury or Poisoning
2310015B14RIK: [Spanning more than 15 kb, the widely expressed human NY-BR-84 Gene at 20pter-q12 encodes a protein of unknown function similar to acyl-CoA thioesterase (C. elegans) and serologically defined breast cancer antigen 84 (Mouse). (from SWISS-PROT, LocusLink, and NCI) ( NCI )] (UMLS (NCI) C1704857) C20orf47;;CGI-54;;dJ477O4.2;;ERGIC and Golgi 3 wt Allele;;ERGIC3 wt Allele;;Erv46;;NY-BR-84;;PRO0989;;SDBCAG84;;Serologically Defined Breast Cancer Antigen 84 Gene =Gene or Genome
2B: [A clinical research protocol generally refered to as a well-controlled and pivotal trial that aims to prove the mechanism of action of the new intervention in question. A pivotal study will generally be well-controlled, randomized, of adequate size, and whenever possible, double-blind. ( NCI )] (UMLS (NCI) C1706096) Phase IIb Trial;;Trial Phase 2B;;Trial Phase IIB =Research Activity
2B1: [A monoclonal antibody with potential antineoplastic activity. Specific for both the immunoglobulin G (IgG) receptor CD16 and c-erbB-2, bispecific antibody 2B1 may enhance cellular immune responses against c-erbB-2-positive cells, resulting in increased tumor cell lysis. (NCI04) ( NCI )] (UMLS (NCI) C0338223) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
2beta,16beta-Dipiperidino-5alpha-androstane-3alpha,17beta-diol Diacetate Dimethobromide: [The bromide salt form of pancuronium, a synthetic, long-acting ammonio steroid muscle relaxant with curarimimetic, some antimuscarinic and sympathomimetic effects. Pancuronium bromide competitively binds to the nicotinic receptor at the neuromuscular junction, thereby preventing acetylcholine binding and resulting in skeletal muscle relaxation and paralysis. ( NCI )] (UMLS (NCI) C0030311) =Steroid; Pharmacologic Substance ;; =PANCURONIUM;; =PANCURONIUM BROMIDE 1 MG/ML;;PANCURONIUM BROMIDE 2 MG/ML
3,3'-[(1,1'-Biphenyl)-4,4'-Diylbis(Azo)]Bis(5-Amino-4-Hydroxy)- 2,7-Naphthalenedisulfonic Acid, Tetrasodium Salt: [A Benzidine-based azo dye that is metabolized to free Benzidine in vivo. Direct blue 6 is primarily used for the dyeing of textiles, leather and paper. Benzidine and its metabolic derivatives have been detected in the urine of workers exposed to Benzidine-based dyes. Exposure to this dye is strongly associated with the occurrence of bladder cancer. (NCI05) ( NCI )] (UMLS (NCI) C0058439) =Organic Chemical; Pharmacologic Substance ;;
3,4-Benzpyrene: [A crystalline, aromatic hydrocarbon consisting of five fused benzene rings and formed during the incomplete combustion of organic matter. 3,4-Benzpyrene is primarily found in gasoline and diesel exhaust, cigarette smoke, coal tar and coal tar pitch, charcoal-broiled foods and certain other foods, amino acids, fatty acids and carbohydrate pyrolysis products, soot smoke, creosote oil, petroleum asphalt and shale oils. This substance is used only for research purposes. 3,4-Benzpyrene is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0005052) =Organic Chemical; Hazardous or Poisonous Substance
3,5-Bis(acetylamino)-2,4,6-triiodobenzoic Acid: [A commonly used x-ray contrast medium. As DIATRIZOATE MEGLUMINE and as Diatrizoate sodium, it is used for gastrointestinal studies, angiography, and urography. ( MSH )] (UMLS (NCI) C0012004) =Organic Chemical; Indicator, Reagent, or Diagnostic Aid ;; =[DX102] IONIC CONTRAST MEDIA;; =1-Deoxy-1-(methylamino)-D-glucitol 3,5-diacetamido-2,4,6-triiodobenzoate (salt);;3,5-Diacetamido-2,4,6-triiodobenzoic Acid, Sodium Salt
3,6-bis-(2-piperidinoethoxyl)acridine trihydrochloride: (UMLS (NCI) C0055843) =Organic Chemical; Pharmacologic Substance ;;
30-39% BDY BRN/10-19% 3D: [ ] (UMLS (ICD9CM) C0161338) =Injury or Poisoning
30-39% BDY BRN/20-29% 3D: [ ] (UMLS (ICD9CM) C0161339) =Injury or Poisoning
30-39% BDY BRN/3 DEG NOS: [ ] (UMLS (ICD9CM) C0161337) =Injury or Poisoning
30-39% BDY BRN/30-39% 3D: [ ] (UMLS (ICD9CM) C0161340) =Injury or Poisoning
3B: [A type of Phase III trial executed near the time of approval to elicit additional findings. This type of trial may be required as a condition of regulatory authority approval. ( NCI )] (UMLS (NCI) C1706097) Phase IIIb Trial;;Trial Phase 3B;;Trial Phase IIIB =Research Activity
3B-O-(4-O-Acetyl-2,6-dideoxy-3-C-methyl-alpha-L-arabino-hexopyranosyl)-7-methylolivomycin D: [A glycosidic antineoplastic antibiotic isolated from the bacterium Streptomyces griseus. Chromomycin A3 reversibly binds to guanine-cytosine (G-C) base pairs in the minor groove of DNA, thereby inhibiting RNA synthesis. This agent is used as a fluorescent chromosome dye. (NCI04) ( NCI )] (UMLS (NCI) C0040563) =Organic Chemical; Antibiotic
3beta-Hydroxy-11-oxoolean-12-en-30-oic Acid Hydrogen cis-1,2-cyclohexanedicarboxylate: (UMLS (NCI) C0055717) =Organic Chemical; Pharmacologic Substance ;;
3beta-Hydroxyandrost-5-en-17-one: [major C19 steroid produced by the adrenal cortex; also produced in small quantities in the testis and the ovary; dehydroepiandrosterone (DHEA) can be converted to testosterone; androstenedione; estradiol; and estrone; most of DHEA is sulfated (dehydroepiandrosterone sulfate) before secretion. ( CSP )] (UMLS (NCI) C0011185) =Steroid; Pharmacologic Substance; Hormone =adrenal cortex hormone;;androgen;;[HS000] HORMONES / SYNTHETICS / MODIFIERS;;Unclassified Ingredients =DEHYDROEPIANDROSTERONE (DHEA) CAP/TAB;;
3beta-N-1-(N-(3-(4-Aminobutyl))-1,3-diaminopropane)-7alpha,24-dihydroxy-5alpha-cholestane 24-sulfate: (UMLS (NCI) C0213314) =Steroid; Pharmacologic Substance
4,4'-Bis(dimethylamino)diphenylmethane: [A yellow colored, combustible leaflet material that emits toxic fumes of nitrogen oxides when heated to decomposition. Michler's base is used as a chemical intermediate in the manufacture of dyes and for its hydrochloric salt and is also used as an analytical reagent in the determination of lead. Exposure to Michler's base irritates the skin and eyes and can lead to methemoglobinemia and respiratory tract distress. Michler's base is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0067320) =Organic Chemical; Pharmacologic Substance ;;
4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide Monohydrochloride: [The hydrochloride salt form of minocycline, a broad-spectrum, semi-synthetic tetracycline antibiotic with antimicrobial properties. Minocycline hydrochloride exerts its bacteriostatic effect by binding to bacterial 30S ribosomal subunit and prevents binding of aminoacyl-tRNA to mRNA on the ribosomes during elongation step of protein translation. This leads to an inhibition of bacterial protein synthesis and consequently cell growth. ( NCI )] (UMLS (NCI) C0026186) =Organic Chemical; Antibiotic =MINOCYCLINE;; =MINOCYCLINE HYDROCHLORIDE 50 MG;;MINOCYCLINE HYDROCHLORIDE 100 MG;;MINOCYCLINE HYDROCHLORIDE 75 MG;;MINOCYCLINE HYDROCHLORIDE 50 MG/5ML;;MINOCYCLINE HYDROCHLORIDE 1 MG
4-(3'-bromoanilino)-6,7-dimethoxyquinazoline: [A protein tyrosine kinase inhibitor that has specific activity for the epidermal growth factor receptor. (NCI) ( NCI )] (UMLS (NCI) C0258113) =Organic Chemical; Pharmacologic Substance
4-(3,5-Bis-(hydroxy-phenyl)-1,2,4)triazol-1-yl)-benzoic Acid: [A synthetic, orally available, achiral, tridentate triazole derived from salicylic acid with iron chelator properties. Deferasirox chelates iron at a 2:1 (ligand:iron) ratio. Because of its oral availablity,and long plasma half-life, this agent may be superior to desferrioxamine (desferal, DFO), which is orally inactive and has a short plasma half-life. ( NCI )] (UMLS (NCI) C1619629) Deferasirox =Organic Chemical; Pharmacologic Substance ;;
4-1BB-Dependent Immune Response Pathway: [The activation of T cells requires a co-stimulatory signal with T cell receptor activation, provided in many cases by activation of CD28 in resting T cells. 4-1BB (CD137) is a member of the TNF receptor gene family that provides another T cell co-stimulatory signal. 4-1BB is expressed by activated cytotoxic and helper T cells and its expression is induced by a variety of T cell stimuli, including activation of the T cell receptor or stimulation with mitogens. The ligand for 4-1BB (4-1BBL) is induced on activated antigen-presenting cells including macrophages, activating T cells More…
4-[(3-Bromophenyl)amino]-6-Acrylamidoquinazoline: [A quinazolone compound with anti-tumor activity. PD-168393 is a cell-permeable, irreversible, and selective inhibitor of ligand-dependent epidermal growth factor (EGF) receptor (EGFR). This agent binds to the catalytic domain of EGFR with a 1:1 stoichiometry and inactivates the EGFR tyrosine kinase activity through alkylation of a cystine residue (Cys-773) within the ATP-binding pocket, thereby inhibiting proliferation of EGFR-expressing tumor cells. ( NCI )] (UMLS (NCI) C1518781) PD 168 393;;PD-168393 =Organic Chemical; Pharmacologic Substance ;;
4-[bis(2-chloroethyl)amino]-L-phenylalanine: [4-bis-(2-chloroethyl)amino-L-phenylalanine; a bifunctional alkylating agent used as a DNA strand crosslinker and antineoplastic. ( CSP )] (UMLS (NCI) C0025241) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;; =[AN000] ANTINEOPLASTICS;;Bis(2-chloroethyl)methylamine;;Nitrogen Mustard Compound;;phenylalanine;;Antineoplastic Alkylating Agent;; =3-(p-(bis(2-chloroethyl)amino)phenyl)-L-Alanine, Hydrochloride;;MELPHALAN 2 MG;;
40-49% BDY BRN/10-19% 3D: [ ] (UMLS (ICD9CM) C0161343) =Injury or Poisoning
40-49% BDY BRN/20-29% 3D: [ ] (UMLS (ICD9CM) C0161344) =Injury or Poisoning
40-49% BDY BRN/3 DEG NOS: [ ] (UMLS (ICD9CM) C0161342) =Injury or Poisoning
40-49% BDY BRN/30-39% 3D: [ ] (UMLS (ICD9CM) C0161345) =Injury or Poisoning
40-49% BDY BRN/40-49% 3D: [ ] (UMLS (ICD9CM) C0161346) =Injury or Poisoning
4B5 monoclonal antibody anti-idiotype vaccine: [A humanized anti-idiotypic (anti-Id) monoclonal antibody (MoAb) that mimics the disialoganglioside GD2, a cancer-associated antigen present on melanoma, small cell lung cancer, sarcoma, neuroblastoma and other malignancies. GD2 is a highly expressed glycosphingolipid by melanoma and other neuroectodermal tumors with only minimal expression on normal tissues. Vaccination with anti-Id 4B5 IgG was capable of eliciting both cellular and humoral immune responses against GD2 expression tumor cells. ( NCI )] (UMLS (NCI) C0879386) MoAb 4B5 anti-idiotype vaccine;;Monoclonal Antibody 4B5 Anti-Idiotype Vaccine =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
5 Benzagel: [ ] (UMLS (RXNORM) C0305090) =Organic Chemical; Pharmacologic Substance ;;
5 Benzagel 0.05 MG/MG Topical Gel: [ ] (UMLS (RXNORM) C0710065) =Clinical Drug
5 bromodeoxycytidine: [5-Bromo-2'-deoxycytidine. Can be incorporated into DNA in the presence of DNA polymerase, replacing dCTP. ( MSH )] (UMLS (CSP) C0006232) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance
5 bromodeoxyuridine: [nucleoside that substitutes for thymidine in DNA and thus acts as an antimetabolite; causes breaks in chromosomes and has been proposed as an antiviral and antineoplastic agent; it has been given orphan drug status for use in the treatment of primary brain tumors. ( CSP )] (UMLS (CSP) C0006233) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance =deoxyuridine;;halocarbon compound;;nucleoside analog;;
5 bromouracil: [5-bromo-2,4(1H,3H)-pyrimidinedione; brominated derivative of uracil that acts as an antimetabolite, substituting for thymine in DNA; used mainly as an experimental mutagen. ( CSP )] (UMLS (CSP) C0006242) =Nucleic Acid, Nucleoside, or Nucleotide; Hazardous or Poisonous Substance =uracil analog;;
5-(2-(4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihydro-2H-Indol-2-one Monohydrochloride: [The hydrochloride salt form of ziprasidone, a benzothiazolylpiperazine derivative and an atypical antipsychotic agent with an antischizophrenic property. Ziprasidone hydrochloride functions as an antagonist at the dopamine D2 and serotonin 5-HT2A and 5-HT1D receptors, and as an agonist at the 5-HT1A receptor. Ziprasidone hydrochloride also inhibits synaptic reuptake of serotonin and norepinephrine. The mechanism of action by which ziprasidone hydrochloride exerts its antischizophrenic effect is unknown but is potentially mediated through a combination of dopamine D2 and serotonin 5-HT2 antagonism. This agent also has antagonistic activity against histamine H1 and alpha-1-adrenergic receptors. ( NCI )] (UMLS (NCI) C0380392) =Organic Chemical; Pharmacologic Substance ;;
5-(bis-(2-Chloroethyl) Amino) Uracil: [Nitrogen mustard derivative of URACIL. It is a alkylating antineoplastic agent that is used in lymphatic malignancies, and causes mainly gastrointestinal and bone marrow damage. ( MSH )] (UMLS (NCI) C0041920) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;; =Nitrogen Mustard Compound;;2, 4-Dioxopyrimidine;;Antineoplastic Alkylating Agent;;
5-[3, 3-Bis(2-chloroethyl)-1-triazeno]imidazole-4-carboxamide: [A synthetic derivative of imidazole with potent antineoplastic properties. Imidazole mustard alkylates DNA, preferentially at guanine residues, resulting in DNA interstrand crosslinks and inhibition of DNA replication and RNA and protein synthesis. (NCI04) ( NCI )] (UMLS (NCI) C0063382) =Organic Chemical; Pharmacologic Substance
5-[[2-(2-Butoxyethoxy)ethoxy]methyl]-6-propyl-1,3-benzodioxole: [A synthetic derivative of benzodioxole and used as an insecticide synergist, Piperonyl Butoxide enhances the active properties of pyrethrin, pyrethroid, rotenone, and carbamate pesticide ingredients by inhibiting insect microsomal enzyme detoxification activity. It is toxic and suspected of causing anorexia, carcinogenesis, convulsions, and dermal irritation, as well as hepatic and renal damage. (NCI04) ( NCI )] (UMLS (NCI) C0031962) =Organic Chemical; Hazardous or Poisonous Substance =Dioxoles;;Pediculicide =PIPERONYL BUTOXIDE TECHNICAL;;PIPERONYL BUTOXIDE 3 %;;
50-59% BDY BRN/10-19% 3D: [ ] (UMLS (ICD9CM) C0161349) =Injury or Poisoning
50-59% BDY BRN/20-29% 3D: [ ] (UMLS (ICD9CM) C0161350) =Injury or Poisoning
50-59% BDY BRN/3 DEG NOS: [ ] (UMLS (ICD9CM) C0161348) =Injury or Poisoning
50-59% BDY BRN/30-39% 3D: [ ] (UMLS (ICD9CM) C0161351) =Injury or Poisoning
50-59% BDY BRN/40-49% 3D: [ ] (UMLS (ICD9CM) C0161352) =Injury or Poisoning
50-59% BDY BRN/50-59% 3D: [ ] (UMLS (ICD9CM) C0161353) =Injury or Poisoning
6,7 benzomorphan: [ ] (UMLS (CSP) C0178433) =Organic Chemical ;; =morphinan;; =cyclazocine;;PENTAZOCINE
60-69% BDY BRN/10-19% 3D: [ ] (UMLS (ICD9CM) C0161356) =Injury or Poisoning
60-69% BDY BRN/20-29% 3D: [ ] (UMLS (ICD9CM) C0161357) =Injury or Poisoning
60-69% BDY BRN/3 DEG NOS: [ ] (UMLS (ICD9CM) C0161355) =Injury or Poisoning
60-69% BDY BRN/30-39% 3D: [ ] (UMLS (ICD9CM) C0161358) =Injury or Poisoning
60-69% BDY BRN/40-49% 3D: [ ] (UMLS (ICD9CM) C0161359) =Injury or Poisoning
60-69% BDY BRN/50-59% 3D: [ ] (UMLS (ICD9CM) C0161360) =Injury or Poisoning
60-69% BDY BRN/60-69% 3D: [ ] (UMLS (ICD9CM) C0161361) =Injury or Poisoning
60B8AG: [Human S100A9 wild-type allele is located within 1q21 and is approximately 3 kb in length. This allele, which encodes S100-A9 protein, plays a role in several cellular processes such as cell cycle progression and differentiation and may play a role in protein kinase inhibition. ( NCI )] (UMLS (NCI) C1704874) CAGB;;CFAG;;CGCB;;L1AG;;LIAG;;MAC387;;MIF;;MRP14;;NIF;;P14;;S100 Calcium Binding Protein A9 (Calgranulin B) wt Allele;;S100A9;;S100A9 wt Allele =Gene or Genome ◊ [Human S100A8 wild-type allele is located within 1q21 and is approximately 1 kb in length. This allele, which encodes S100-A8 protein, is involved in cell cycle progression and differentiation and may play a role in casein kinase inhibition. ( NCI )] (UMLS (NCI) C1704875) CAGA;;CFAG;;CGLA;;CP-10;;L1Ag;;MA387;;MIF;;MRP8;;NIF;;P8;;S100 Calcium Binding Protein A8 (Calgranulin A) wt Allele;;S100A8;;S100A8 wt Allele Gene or Genome
7 Benzyloxyresorufin O Dealkylase: [A major cytochrome P-450 enzyme which is inducible by PHENOBARBITAL in both the LIVER and SMALL INTESTINE. It is active in the metabolism of compounds like pentoxyresorufin, TESTOSTERONE, and ANDROSTENEDIONE. This enzyme, encoded by CYP2B1 gene, also mediates the activation of CYCLOPHOSPHAMIDE and IFOSFAMIDE to MUTAGENS.(MSH)] (UMLS (NDFRT)) (C0070319) =Amino Acid, Peptide, or Protein; Enzyme ;; =aryl 4 monooxygenase;;
70-79% BDY BRN/10-19% 3D: [ ] (UMLS (ICD9CM) C0161364) =Injury or Poisoning
70-79% BDY BRN/20-29% 3D: [ ] (UMLS (ICD9CM) C0161365) =Injury or Poisoning
70-79% BDY BRN/3 DEG NOS: [ ] (UMLS (ICD9CM) C0161363) =Injury or Poisoning
70-79% BDY BRN/30-39% 3D: [ ] (UMLS (ICD9CM) C0161366) =Injury or Poisoning
70-79% BDY BRN/40-49% 3D: [ ] (UMLS (ICD9CM) C0161367) =Injury or Poisoning
70-79% BDY BRN/50-59% 3D: [ ] (UMLS (ICD9CM) C0161368) =Injury or Poisoning
70-79% BDY BRN/60-69% 3D: [ ] (UMLS (ICD9CM) C0161369) =Injury or Poisoning
70-79% BDY BRN/70-79% 3D: [ ] (UMLS (ICD9CM) C0161370) =Injury or Poisoning
7B4: [Human CDH5 wild-type allele is located in the vicinity of 16q22.1 and is approximately 38 kb in length. This allele, which encodes vascular endothelial-cadherin protein, plays a role in calcium-dependent cell-cell adhesion, endothelial cell cohesion and endothelial survival. ( NCI )] (UMLS (NCI) C1707111) Cadherin 5, Type 2, VE-Cadherin (Vascular Epithelium) wt Allele;;CDH5 wt Allele =Gene or Genome
7B4 Antigen: [Encoded by human CDH5 Gene (CDH Family), 784-amino acid 87.5 kD (precursor) Vascular Endothelial Cadherin is a Ca(2+)-dependent homophilic endothelial cell-cell adhesion type I membrane glycoprotein composed of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. Expressed specifically in endothelial cells and brain, VE-Cadherin is found mainly at cell-cell boundaries, associated with intercellular junctions. CDH5 may play a role in endothelial cell cohesion and organization of intercellular junctions. CDH5/beta-catenin signaling may control endothelial survival. CDH5 associates with alpha-catenin, forming a link to the cytoskeleton. (from LocusLink, SWISS-PROT, OMIM, and NCI) ( NCI )] (UMLS (NCI) C0300423) =Amino Acid, Peptide, or Protein; Immunologic Factor
7beta-Hydroxyfluasterone: (UMLS (NCI) C1883650) =Steroid; Pharmacologic Substance; Hormone
80-89% BDY BRN/10-19% 3D: [ ] (UMLS (ICD9CM) C0161373) =Injury or Poisoning
80-89% BDY BRN/20-29% 3D: [ ] (UMLS (ICD9CM) C0161374) =Injury or Poisoning
80-89% BDY BRN/3 DEG NOS: [ ] (UMLS (ICD9CM) C0161372) =Injury or Poisoning
80-89% BDY BRN/30-39% 3D: [ ] (UMLS (ICD9CM) C0161375) =Injury or Poisoning
80-89% BDY BRN/40-49% 3D: [ ] (UMLS (ICD9CM) C0161376) =Injury or Poisoning
80-89% BDY BRN/50-59% 3D: [ ] (UMLS (ICD9CM) C0161377) =Injury or Poisoning
80-89% BDY BRN/60-69% 3D: [ ] (UMLS (ICD9CM) C0161378) =Injury or Poisoning
80-89% BDY BRN/70-79% 3D: [ ] (UMLS (ICD9CM) C0161379) =Injury or Poisoning
80-89% BDY BRN/80-89% 3D: [ ] (UMLS (ICD9CM) C0161380) =Injury or Poisoning
851B Gel: [A topical gel containing a peptide derived from the human papillomavirus (HPV). Application of 851B gel may stimulate the host immune system to trigger a cytotoxic T-lymphocyte response to cells that express HPV. ( NCI )] (UMLS (NCI) C1711061) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
88BV59H21-2V67-66: (UMLS (NCI) C1527204) =Amino Acid, Peptide, or Protein; Pharmacologic Substance ;;
8B-[(Methylthio)methyl]-6-propylergoline Monomethanesulfonate: [A semi-synthetic ergot derivative and a dopamine agonist with antiparkinson property. Pergolide mesylate binds to and activates dopamine receptor subtypes D1 and D2, resulting in prolactin secretion inhibition, transient increase in serum concentration of growth hormone, and decrease in serum concentration of luteinizing hormone. Direct stimulation of postsynaptic dopamine receptors in the nigrostriatal system, may account for this agent's antiparkinson activity. ( NCI )] (UMLS (NCI) C0031008) =Organic Chemical; Pharmacologic Substance =PERGOLIDE;; =PERGOLIDE MESYLATE 0.05 MG;;PERGOLIDE MESYLATE 0.25 MG;;PERGOLIDE MESYLATE 1 MG
9,13b-Dihydro-1H-dibenz(c,f)imidazo(1,5-a)azepin-3-amine Hydrochloride: [An histamine H1 receptor antagonist without sedative activity. Epinastine hydrochloride blocks the histamine H1 receptor and inhibits the release of histamine from mast cells. This prevents the typical allergic symptoms that are caused by histamine activity on capillaries, skin, mucous membranes, and on gastrointestinal and bronchial smooth muscles. Typical histamine activities include vasodilation, bronchoconstriction, increased vascular permeability, pain, itching, and spasmodic contractions of gastrointestinal smooth muscles. Epinastine also has affinity for the histamine H2, 5-HT2, and the alpha-1, alpha-2 adrenergic receptors. ( NCI )] (UMLS (NCI) C0772294) Alesion;;Epinastine Hydrochloride;; =Organic Chemical; Pharmacologic Substance ;;
9-Beta-D-arabinofuranosyl-9H-purine-6-amine Monohydrate: [A nucleoside antibiotic isolated from the bacterium Streptomyces antibioticus with antineoplastic activity. Vidarabine inhibits DNA polymerase, resulting in the inhibition of DNA replication in tumor cells. (NCI04) ( NCI )] (UMLS (NCI) C0042646) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;; =adenosine;;arabinonucleoside;;[OP203] ANTIVIRALS, TOPICAL OPHTHALMIC;; =2-Fluoro-9-beta-arabinofuranosyladenine;;VIDARABINE 3 %;;
90% + BDY BRN/10-19% 3RD: [ ] (UMLS (ICD9CM) C0161383) =Injury or Poisoning
90% + BDY BRN/20-29% 3RD: [ ] (UMLS (ICD9CM) C0161384) =Injury or Poisoning

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