[Sp1 Activation Cofactor Genes encode (at least 9) protein subunits of the CRSP (Cofactor Required for SP1 activation) complex, which, along with TFIID, is required for efficient activation of gene transcription by SP1, a transcription factor that recognizes enhancer sites in target DNA. Many CRSP complex proteins are also components of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins that interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. (NCI) ( NCI )] (UMLS (NCI) C1336035) =Gene or Genome ;;
[Disorder characterized by nausea, vomiting, and dizziness, possibly in response to vestibular disorientation or fluid shifts associated with space flight. (From Webster's New World Dictionary)(MSH)] (UMLS (NDFRT)) (C0242700) =Disease or Syndrome ;; =Motion sickness;;
[This gene plays a role in the modulation of cell adhesion of spermatozoa. ( NCI )] (UMLS (NCI) C1335859) SPAM1 Gene;;Sperm Adhesion Molecule 1 (PH-20 Hyaluronidase, Zona Pellucida Binding) Gene =Gene or Genome ;;
[Infection of animals, including fish and man, with a developmental stage of Diphyllobothrium. This stage has recently been referred to as a plerocercoid but the name sparganum has persisted. Therefore, infection of fish or other animals with the plerocercoid larvae is sparganosis. Fish-eating mammals, including man, are the final hosts. ( MSH )] (UMLS (ICD9CM) C0037753) =Disease or Syndrome ;; =DIPHYLLOBOTHRIAS INTEST;;
[A prolactin producing pituitary gland adenoma composed of relatively large, chromophobic or slightly acidophilic cells with well developed, abundant endoplasmic reticulum, and many immature secretory granules. Mature secretory granules are sparse. (NCI05) ( NCI )] (UMLS (NCI) C1710139) =Neoplastic Process
[An antitumor antibiotic produced by Streptomyces sparsogenes. It inhibits protein synthesis in 70S and 80S ribosomal systems. ( MSH )] (UMLS (CSP) C0037759) =Organic Chemical; Antibiotic
[A quinolizidine alkaloid isolated from several FABACEAE including LUPINUS; SPARTIUM; and CYTISUS. It has been used as an oxytocic and an anti-arrhythmia agent. It has also been of interest as an indicator of CYP2D6 genotype. ( MSH )] (UMLS (CSP) C0037760) =Organic Chemical; Pharmacologic Substance
[A twisted neck symptom that is caused by the spasmodic involuntary muscle contractions in the neck region. ( MSH )] (UMLS (ICD9CM) C0152116) =Sign or Symptom ;;
[paralysis marked by spasticity of the muscles of the paralyzed part and increases tendon reflexes, due to upper motor neuron lesions. ( CSP )] (UMLS (CSP) C0085621) =Pathologic Function =paralysis;;
[Refers to the ways in which objects or bodies are placed in space and in relation to each other. ( NCI )] (UMLS (NCI) C0681263) =Intellectual Product ;;