Medical glossary.
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(+)-2-(2-((p-Chloro-alpha-methyl-alpha-phenylbenzyl)oxy)ethyl)-1-methyl Pyrrolidine Fumarate
[A synthetic ethanolamine with anticholinergic, sedative, and histamine H1 antagonistic properties. Clemastine fumarate blocks the H1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial and gastrointestinal smooth muscles, including vasodilation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscles. This drug also prevents histamine-induced pain and itching of mucous More…
(+)-2-(p-Chloro-alpha-(2-(dimethylamino)ethyl)benzyl)pyridine Maleate(1:1)
[The maleate salt form of dexchlorpheniramine, an alkylamine, and first-generation histamine antagonist with anti-allergic activity. Dexchlorpheniramine maleate competitively blocks H1 receptors, thereby preventing the actions of histamine on bronchial smooth muscle, capillaries and gastrointestinal (GI) smooth muscle. This prevents histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, and GI smooth muscle spasms. ( NCI )] (UMLS (NCI) C0137440) More…
(-)-Phenylisopropylmethylpropynylamine
[The hydrochloride salt form of selegiline, a levorotatory acetylenic derivative of phenethylamine with antiparkinsonian effect. As a selective monoamine oxidase (MAO) inhibitor, selegiline has the greatest affinity for type B MAO, found mainly in the brain. Selegiline is converted by MAO B to an active moiety, which binds irreversibly at the active site of the enzyme's cofactor FAD (flavin adenine dinucleotide) molecule. This prevents the oxidative deamination of catecholamines and More…
(.+ -.)-p-Isobutylhydratropic acid
[nonsteroidal analgesic, antipyretic and anti-inflammatory agent that is a propionic acid derivative. ( CSP )] (UMLS (NCI) C0020740) =Organic Chemical; Pharmacologic Substance ;; =[CN100] ANALGESICS;;NSAIDs;;[CN850] ANTIPYRETICS;;benzoate;;Phenylpropionates;;[MS102] NONSALICYLATE NSAIS, ANTIRHEUMATIC;;[CN104] NONSTEROIDAL ANTI-INFLAMMATORY ANALGESICS;; =IBUPROFEN 100 MG;;IBUPROFEN 100 MG/5ML;;IBUPROFEN 200 MG;;IBUPROFEN 300 MG;;IBUPROFEN 600 MG;;IBUPROFEN 800 MG;;IBUPROFEN 400 MG;; More…
(p-Methoxyphenyl)trithiopropene
[A drug that may reduce the risk of development or progression of cancer. ( NCI )] (UMLS (NCI) C0002937) =Organic Chemical; Pharmacologic Substance
*Pressure (Partial)
(UMLS (HL7) C0030604) =Natural Phenomenon or Process ;; =Kind of quantity;;
1,1',1"-phosphinothioylidynetrisaziridine
[alkylating agent used as an antineoplastic in the treatment of carcinoma of the breast, ovary, and bladder, malignant infusions and lymphomas. ( CSP )] (UMLS (NCI) C0039871) =Organophosphorus Compound; Pharmacologic Substance; Hazardous or Poisonous Substance =[AN000] ANTINEOPLASTICS;;Organothiophosphorus Compounds;;Triethylenephosphoramide;;Aminoethylene;;Antineoplastic Alkylating Agent;; =THIOTEPA 15 MG
1,1'-[1,4-Phenylenebis(methylene)]-bis-1,4,8,11-tetraazacyclotetradecane
(UMLS (NCI) C1527080) Bis(Tetraazacyclotetradecane) Derivative;; =Organic Chemical; Pharmacologic Substance
1,1,1,3,3-Pentafluoropropane/Norflurane Topical application Spray [SPRAY AND STRETCH]
[ ] (UMLS (RXNORM) C1698649) (1,1,1,3,3-Pentafluoropropane/Norflurane Topical Spray [SPRAY AND STRETCH]) 1,1,1,3,3-Pentafluoropropane/Norflurane Topical Spray [SPRAY AND STRETCH] =Clinical Drug
1,10-(1,2-Phenylene)pyrene
[A yellowish, aromatic hydrocarbon consisting of six fused rings and produced by the incomplete combustion of organic matter. Indene[1,2,3-cd]pyrene is primarily found in certain foods, gasoline and diesel exhaust, cigarette smoke, coal tar and coal tar pitch, soot and petroleum asphalt. This substance is used only for research purposes. Indene[1,2,3-cd]pyrene is reasonably anticipated to be a human carcinogen. (NCI05) ( NCI )] (UMLS (NCI) C0063458) =Organic Chemical; Pharmacologic More…
1,2,3-Propanetricarboxylic Acid, 2-hydroxy-, Gallium-(sup 67)Ga(1:1) Salt
[A radioactive salt of gallium used as a radiopharmaceutical. The exact mechanism of action is unknown, but gallium citrate Ga-67 has been found to concentrate in certain viable primary and metastatic tumors as well as focal sites of inflammation. Adequate blood supply is essential for delivery of gallium citrate Ga-67 to the lesion. Gallium citrate Ga-67 is used as a diagnostic tool in neoplastic disease and inflammatory lesions. (NCI05) ( NCI )] (UMLS (NCI) C0893383) Gallium 67 More…
1,2,3-Propanetriol
[1,2,3-trihydroxypropane, a key intermediate in glucose metabolism; also serves as the bridge between hydrophobic "tails" and hydrophilic "heads" of many membrane lipids; reagent is used as a water-soluble solvent and lubricant. ( CSP )] (UMLS (NCI) C0017861) =Organic Chemical; Pharmacologic Substance; Biologically Active Substance =[DE350] EMOLLIENTS;;sugar alcohol;;triose;;[OP106] OSMOTIC AGENTS, SYSTEMIC OPHTHALMIC;;[RS300] LAXATIVES, RECTAL;;[OP500] EYE More…
1,2,3-Propanetriyl Butanoate
[A triglyceride drug that may inhibit cell growth and induce cell differentiation. Differentiating agents may be effective in changing cancer cells back into normal cells. ( NCI )] (UMLS (NCI) C0077025) =Lipid; Pharmacologic Substance ;;
1,2-Propyleneimine
[A synthetic, flammable, volatile, colorless oily liquid that is soluble in water, ethanol and most organic solvents. Propylenimine is used in the United States exclusively as an intermediate, and its derivatives are used in the paper, textile, rubber and pharmaceutical industries. Due to its volatility, potential exposure could occur during production, packaging, or use of substances made with this liquid. The primary routes of potential human exposure to propylenimine are inhalation, More…
1,3-Propanediol, 2-((3-fluoranthenylmethyl)amino)-2-methyl-
(UMLS (NCI) C0100007) =Organic Chemical; Pharmacologic Substance ;;
1,3-Propanediol, 2-Amino-2-(hydroxymethyl)-
[A member of the pyrrolo-pyrrole group of non-steroidal anti-inflammatory drugs (NSAID) with analgesic, anti-inflammatory, and anti-pyretic properties. Tromethamine inhibits both isoforms of cyclooxygenases (COX1 and COX2), thereby blocking the conversion of arachidonic acid to pro-inflammatory pro-prostaglandins. When inhibiting COX2, tromethamine may be effective in relieving pain and inflammation; when inhibiting COX1, this agent may produce unacceptable gastrointestinal side effects. More…
1,3-Propanediol, 2-methyl-2-propyl-, Dicarbamate
[A carbamate derivate with hypnotic, anti-anxiety, sedative, anticonvulsant and some indirect muscle relaxant properties. Although the exact mechanism of meprobamate is largely unknown, it appears to act as a depressant at multiple sites in the central nervous system, mostly likely through the GABAergic neurotransmitter system, including the thalamus and limbic system. ( NCI )] (UMLS (NCI) C0025386) =Organic Chemical; Pharmacologic Substance ;; =carbamate;;[CN309] More…
1,4-Pentanediamine, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-, Phosphate (1:2)
[The phosphate salt of chloroquine, a quinoline compound with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum. Although the mechanism of action is not fully understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the More…
1,4-Phenylenebis(methylene)selenocyanate
(UMLS (NCI) C0167369) =Organic Chemical; Pharmacologic Substance ;;
1,4-Pregnadiene-2,20-dione-16,17-cyclopentylidenedioxy-9-fluoro-11,21-dihydroxy-21-acetate
[A synthetic glucocorticoid receptor agonist that mimics the metabolic, anti-inflammatory, and immunosuppressive activity of the natural glucocorticoids. Amcinonide interacts with specific corticosteroid receptors and was internalized, which leads to binding of DNA and modification of gene expression. This results in synthesis of anti-inflammatory mediators while inhibiting synthesis of inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune More…
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