[A propylamine derivative with sympathomimetic property. Propylhexedrine binds to and activates alpha-adrenergic receptors in the mucosa of the respiratory tract, thereby mimicking the actions of norepinephrine and epinephrine. This results in vasoconstriction and reduces swelling and inflammation of the mucous membrane lining, therefore relieving nasal and sinus congestion. ( NCI )] (UMLS (NCI) C0033508) =Organic Chemical; Pharmacologic Substance ;;
[A synthetic derivative of hydroxyurea with antiasthmatic properties. The leukotriene inhibitor zileuton blocks 5-lipoxygenase, which catalyzes the formation of leukotrienes from arachidonic acid; causes bronchodilation; decreases bronchial mucous secretion and edema; and may prevent or decrease the symptoms of asthma. (NCI04) ( NCI )] (UMLS (NCI) C0081408) =Organic Chemical; Pharmacologic Substance =Hydroxycarbamide;;[RE108] ANTIASTHMA, ANTILEUKOTRIENES =ZILEUTON 600 MG;;
[An anticancer drug that belongs to the family of drugs called antiandrogens. ( NCI )] (UMLS (NCI) C0285590) =Organic Chemical; Pharmacologic Substance ;; =Anilides;;[AN000] ANTINEOPLASTICS =BICALUTAMIDE 50 MG
[The hydrochloride salt of atomoxetine, a phenoxy-3-propylamine derivative and selective non-stimulant, norepinephrine reuptake inhibitor with cognitive-enhancing activity. Although its precise mechanism of action is unknown, atomoxetine appears to selectively inhibit the pre-synaptic norepinephrine transporter, resulting in inhibition of the presynaptic reabsorption of norepinephrine and prolongation of norepinephrine activity in the synaptic cleft. The effect on cognitive brain More…
[very poisonous alkaloid; the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission; nicotine is important medically because of its presence in tobacco smoke, and is also used as an insecticide. ( CSP )] (UMLS (NCI) C0028040) =Organic Chemical; Pharmacologic Substance; Hazardous or Poisonous Substance =alkaloid;;pyridine;;Solanaceous Alkaloids;;cholinergic agent;;[AD900] ANTIDOTES/DETERRENTS, More…
[precursor of epinephrine; widespread central and autonomic neurotransmitter, principal transmitter of most postganglionic sympathetic fibers; secreted by the adrenal medulla; used pharmacologically as a sympathomimetic. ( CSP )] (UMLS (NCI) C0028351) =Organic Chemical; Pharmacologic Substance; Neuroreactive Substance or Biogenic Amine =adrenergic agent;;catecholamine;;Adrenal;;Neurotransmitter;;adrenal medulla hormone;;[AU100] SYMPATHOMIMETICS (ADRENERGICS) More…
[A synthetic quinolone and antibacterial agent with urinary tract antiseptic activity. Nalidixic acid concentrates in the renal tubules and bladder and exerts its local antibacterial actions by interference of DNA gyrase activity, thereby inhibiting DNA synthesis during bacterial replication in a dose-dependent manner. Nalidixic acid is active against most gram-negative organisms that cause urinary tract infections. ( NCI )] (UMLS (NCI) C0027353) =Organic Chemical; Pharmacologic More…
[A naturally occurring dicarboxylic acid produced by Malassezia furfur andfound in whole grain cereals, rye, barley and animal products. Azelaic acid possesses antibacterial, keratolytic, comedolytic, and anti-oxidant activity. Azelaic acid is bactericidal against Proprionibacterium acnes and Staphylococcus epidermidis due to its inhibitory effect on the synthesis of microbial cellular proteins. Azelaic acid exerts its keratolytic and comedolytic effects by reducing the thickness of the More…