[A three substituted fluoranthene derivative of the 2-(arylmethylamino)-1,3-propanediol family that intercalates with DNA, causing inhibition of DNA synthesis. (NCI) ( NCI )] (UMLS (NCI) C0280441) =Organic Chemical; Pharmacologic Substance
[Human CDKN1C wild-type allele located in the vicinity of 11p15.5 and is approximately 2 kb in length. This allele, which encodes cyclin-dependent kinase inhibitor 1C protein, plays a negative role in the regulation of cellular proliferation by inhibiting several G1 cyclin/Cdk complexes. Mutations of the gene, which generates variant alleles have been implicated in both sporadic cancers and Beckwith-Wiedemann syndrome, suggesting that it is a tumor suppressor candidate. ( NCI )] (UMLS (NCI) C1706028) BWS;;CDKN1C wt Allele;;Cyclin-Dependent Kinase Inhibitor 1C wt Allele;;KIP2;;KIP2 Gene;;p57;;P57-Kip2 Gene;;WBS =Gene or Genome
[Human SLC22A18 wild-type allele is located in the vicinity of 11p15.5 and is approximately 26 kb in length. This allele, which encodes organic cation transporter-like protein 2, is involved in tumor suppression and may play a role in the transport of organic cations. ( NCI )] (UMLS (NCI) C1704827) BWSCR1A;;HET;;IMPT1;;ITM;;ORCTL2;;p45-BWR1A;;SLC22A18 wt Allele;;SLC22A1L;;SLC22A1L Gene;;Solute Carrier Family 22 (Organic Cation Transporter), Member 18 wt Allele;;TSSC5;; =Gene or Genome