[This gene plays a role in transcriptional regulation through the signal transduction activating transcription pathway or STAT pathway. ( NCI )] (UMLS (NCI) C1334885) NMI Gene; N-MYC (and STAT) Interactor Gene =Gene or Genome ; ◊ [NMYC interactor (NMI) is a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. (LocusLink) ( NCI )] (UMLS (NCI) C1334888) NMYC and STAT Interactor; NMYC Interactor Amino Acid, Peptide, or Protein; Biologically Active Substance